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February 12, 2008

What to avoid if you want to make it to 90

Life Extension Update Exclusive

An article published in the February 11, 2008 issue of the American Medical Association journal Archives of Internal Medicine reveals that avoiding five modifiable factors can significantly increase the odds of living to the age of 90.

Laurel B. Yates, MD, MPH, of Brigham & Women’s Hospital in Boston and associates evaluated data from 2,357 older participants in the Physician’s Health Study, a trial of aspirin and beta-carotene as cardiovascular disease and cancer preventives in 22,071 male physicians. Demographic information, blood pressure, cholesterol levels, diabetes and angina history, exercise frequency, smoking status, body mass index, and other data were obtained upon enrollment between 1981 and 1984. Follow-up questionnaires were completed annually to ascertain changes in health or lifestyle habits, or the occurrence of chronic diseases or risks through March, 2006.

Nine hundred-seventy men in the current investigation survived to age 90 and beyond. The research team identified five controllable factors associated with failure to reach 90: smoking, diabetes, obesity, hypertension, and a sedentary lifestyle.

Not surprisingly, smoking more than doubled the risk of dying before the age of 90. Diabetes, obesity, and hypertension also significantly elevated mortality risk, while regular exercise lowered it by 30 percent compared to those who rarely or never exercised. Men who survived to 90 had a healthier lifestyle, less chronic disease, and were older when disease was diagnosed. They also experienced improved late-life function and well-being.

From the results of this study, the researchers estimated that a 70 year old nondiabetic nonsmoker with normal weight and blood pressure who exercised two to four times per week had a 54 percent probability of living to age 90. The presence of three of the identified risk factors conferred a 14 percent probability, while having all five resulted in only a 4 percent chance.

“Although the impact of certain midlife mortality risks in elderly years is controversial, our study suggests that many remain important, at least among men,” the authors write. “Thus, our results suggest that healthy lifestyle and risk management should be continued in elderly years to reduce mortality and disability.”

In an accompanying editorial, William J. Hall, MD notes that the fastest-growing group of older Americans is aged 85 years and older. “This unprecedented increase of the oldest old is occurring in an era of extraordinary rapid development of new knowledge of the human genome, holding tantalizing promise for novel solutions to human disease and even increased life extension,” he writes. “This study suggests that adherence to sound medical management and lifestyle modification pays enormous dividends in life extension and probably substantial reductions of aggregate medical care costs.”

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February 28-March 2, 2008

The International Hormone Society & the American Academy of Anti-Aging Medicine is proud to present “A Practical Application of Treating Adult Hormone Deficiencies”- (Advanced course). If you are interested in learning more about the use of Hormone Replacement in age management using Bioidentical hormone replacement for yourself and your patients, we highly recommend this course!

This seminar will present the data behind current treatments of aging, and will offer practical treatment programs for your patient, as well as for your own personal health. The program will be presented by David Brownstein MD, Ron Rothenberg MD, Thierry Hertoghe MD, a fourth generation practicing endocrinology physician from Belgium, and Jonathan Wright MD, America’s top physicians in bioidentical hormone replacement will share the stage in the latest treatments in nutrition and hormone therapy. All physicians are practicing physicians and considered some of the leading bioidentical hormone specialists who are currently treating thousands of patients with these current treatments at their own clinics.

To register, call 1-866-444-9475 or visit

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If you have questions or comments concerning this issue or past issues of Life Extension Update, send them to ddye@lifeextension.com or call 954 202 7716.

For longer life,

Dayna Dye
Editor, Life Extension Update
ddye@lifeextension.com
954 766 8433 extension 7716
www.lef.org