Chronic inflammation is also involved in diseases as diverse as atherosclerosis, cancer, heart valve dysfunction, obesity, diabetes, congestive heart failure, digestive system diseases, and Alzheimer's disease (Brouqui et al. 1994; Devaux et al. 1997; De Keyser et al. 1998). In aged people with multiple degenerative diseases, the inflammatory marker, C-reactive protein, is often sharply elevated, indicating the presence of an underlying inflammatory disorder (Invitti 2002; Lee et al. 2002; Santoro et al. 2002; Sitzer et al. 2002). When a cytokine blood profile is conducted on people in a weakened condition, an excess level of one or more of the inflammatory cytokines, e.g., TNF-a, IL-6, IL-1(b), or IL-8, is usually found (Santoro et al. 2002).
In a study published in the July 18, 2001 issue of the Journal of the American Medical Association, a group from the famous Women's Health Study was evaluated to ascertain what risk factors could predict future development of Type II diabetes (Pradhan et al. 2001). The findings showed that baseline levels of C-reactive protein and interleukin-6 (IL-6) were significantly higher among those who subsequently developed diabetes compared to those who did not.
When comparing the highest versus lowest quartile, women with the higher IL-6 levels were 7.5 times more likely to develop diabetes while those in the higher C-reactive protein ranges were 15.7 times more likely to become diabetic. After adjusting for all other known risk factors, women with the highest IL-6 levels were 2.3 times at greater risk, while those with the highest C-reactive protein levels were 4.2 times more likely to become diabetic. It should be noted that these other diabetic risk factors (such as obesity, estrogen replacement therapy and smoking) all sharply increase inflammatory markers in the blood.
Second Annual Life Extension Cruise
The second Life Extension Seminar at Sea will be a 7-night cruise on August 29, 2008. This time we will cruise the splendor of the Alaskan wilderness aboard Celebrity’s sumptuous Infinity. You’ll enjoy our Life Extension seminars, one-on-one consultations, a welcome aboard cocktail reception, exceptional personal service, award-winning cuisine, world-famous amenities, accommodations that are the most spacious at sea, and much more.
Experience the extraordinary: Celebrity
Travel press, such as Condé Nast Traveler, consistently rate Celebrity Cruises as one of the world's finest cruise lines. Celebrity offers an incomparable cruise experience aboard ships of uncompromising style and sophistication. From spectacular dining to indulgent spa treatments, you’ll find countless possibilities to satisfy body and soul. Sleep upon Egyptian cotton linens, enjoy butler service in all suites, or special amenities with Concierge Class staterooms, dine in award-winning restaurants, pay a visit to Fortunes Casino, experience Las Vegas-style shows or a movie in the cinema, be pampered by Celebrity's exclusive AquaSpa programs, and much more.
A Celebrity Alaska cruise represents a thoroughly researched and carefully orchestrated collection of spectacular ports of call and exciting shore and land excursions, all connected by routes through some of the area’s most stunning land marine environments. Your ports of call: Seattle, Washington; Sitka, Alaska; Hubbard Glacier (Cruising); Juneau, Alaska; Ketchikan, Alaska; Victoria, British Columbia; Seattle, Washington.
For reservations or for more information please call Life Extension Vacations at 800-791-4457 or email firstname.lastname@example.org.