Every cancer, including prostate cancer, is a disordered and abnormal cell growth. Cancer cells have lost the ability to network and communicate in the way that normal cells do, and they no longer function as intended in the overall framework of body chemistry. Such cells take on a demeanor of juvenile delinquents, with no respect for parental direction. Attempts to restrict disruptive or nonproductive behavior are ignored. Such disruptive cells are usually censored and expelled by regulatory monitors--guardians of the genome, proteins such as p53, p21, and p27, which normally identify and biologically excise such maladapted cells. In malignant conditions, these regulatory proteins lose control for largely unknown reasons.
In one study involving the development of malignancy of the esophagus, antibodies to p53 were found in 4 of 36 (11%) premalignant lesions of the esophagus and in 10 of 33 (30%) of those with cancer of the esophagus. In two of the esophageal cancer patients, the p53 antibodies were detected prior to a clinical diagnosis of cancer. Therefore, the cellular counterparts of terrorists are finding a way past one of the surveillance mechanisms (p53) that usually stand guard to detect DNA damage and halt the machinery of the cell cycle in G1 or G2 when DNA defects are found.
The development of malignancy results from a combination of hits on the cell--repeated insults. Ongoing promotional and progression events eventually lead to premalignant changes such as prostatic intraepithelial neoplasia (PIN), then to noninvasive cancer, and finally to invasive cancer. If not diagnosed early and eradicated, metastatic cancer may eventually develop.
Life Extension Vacations: Exclusive Offer for Life Extension Members One week villa vacation for only $399 (land only)
Enjoy a fantastic retreat with Life Extension Vacations! A week’s stay for four in one of our showcase resort destinations selected for the variety of amenities and activities they offer:
- Visit beautiful Lake Tahoe, where California and Nevada meet, one of the bluest, purest and clearest bodies of water in the world.
- Experience one of the largest ski mountains in North America, Steamboat Springs (Colorado).
- Relax and breathe in the magical energy and spectacular scenery of Sedona (Arizona).
- Plan to escape to the town of Lincoln (New Hampshire), comprised largely of White Mountain National Forest lands, a special and wonderful place to visit throughout the year.
- Enjoy the magical, mystical and alluring Marco Island in Florida.
- Be inspired with the nearly one million acres of wilderness in Sun Valley, Idaho.
- How about these other options: Phoenix (Arizona), Clarksville (Georgia), Sheridan (Illinois), South Bend (Indiana), South Lee (Massachusetts), Myrtle Beach (South Carolina), Galveston (Texas), Palm Springs or San Francisco (California).
If you want to go further afar, your options include Hawaii, Bahamas, Dominican Republic and Mexico for non-stop beach fun, snorkeling and diving, dolphin swims, boat trips and excursions to historic sites, cultural attractions and nature parks.
We can help you with your airline tickets and car rental too!
All taxes included. Travel dates through December 31, 2008. Mandatory check-in on Saturdays. Based upon availability. Prices subject to change without notice. Other restrictions may apply.
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Life Extension Vacations