Compelling and growing evidence links inflammation and oxidative stress to Alzheimer’s disease. According to the inflammation theory (discussed in dozens of recent clinical trials), inflammatory cytokines gather at the neurons of people who have Alzheimer's. These cytokines set off an inflammatory cascade. The inflammation generates high levels of free radicals that contribute directly to the formation of beta-amyloid plaques. The result is more inflammation, free radicals, and beta-amyloid plaques. Iron has also been linked to the generation of free radicals. Studies have shown that free iron accumulates on the surface of dying neurons, where it generates oxygen-derived free radicals that hasten the spread of the disease (Mandel S et al 2006).
Vitamin E is a powerful antioxidant. Deficiencies of vitamin E in patients who have Alzheimer's disease are associated with increased lipid peroxidation, which appears to cause increased platelet aggregation, a hallmark of Alzheimer's (Ciabattoni G et al 2006). Community studies have shown that high doses of vitamin E, along with vitamin C, may help prevent Alzheimer's disease in the healthy elderly (Landmark K 2006). Combination therapy with vitamins C and E has been shown to reduce lipid peroxidation in people who have mild to moderate Alzheimer’s disease (Galbusera C et al 2004). High doses of vitamin E alone, up to 2000 International Units (IU) daily, slow the mental deterioration of patients who have Alzheimer's disease (Grundman M 2000).
One method by which vitamin E might protect people has to do with its relation to apoE4, which is associated with an increased risk of developing Alzheimer's disease. In people with the apoE4 phenotype, researchers suspect that an impairment in the antioxidant delivery system to neuronal cells may be related to increased oxidative damage (Mas E et al 2006). Another theory suggests that vitamin E might be able to reduce the oxidative damage caused by large amounts of inducible nitric oxide synthase, a pro-oxidant that has been linked to progression of Alzheimer's disease (McCann SM et al 2005).
Bio-identical hormone therapy (BHRT) is finally getting its day in the sun. Top experts in the field will be revealing their approaches and the treatments they use in their busy practices. You'll understand why their patients love them. These are the same experts who write the books, appear on TV and report to Congress.
An opportunity to learn from these physicians is usually open to just doctors at medical conventions. Now you can hear the BHRT World Summit in the comfort of your home! This audio seminar will be presented the evenings of May 14 to 29. We invite you to take advantage of this unique opportunity to hear more then 10 practitioner/experts speak about everything from menopause to prostates, migraines to depression, cancer prevention to thyroid health and many more hormone related conditions.
The public wants to learn and the experts are ready to speak. BHRT is improving lives. Click here to see the doctors, their topics and to register.