Depression is considered the most common cause of disability in the United States (Norman TR 2006). According to the National Institutes of Health, clinical depression will affect up to 25 percent of women in their lifetimes and up to 12 percent of men. People with depression suffer in many areas of their lives, including sleep, eating, relationships, school, work, and self-image.
Treatment for depression is usually multifaceted, and there is no doubt that nutrition plays an important role. Research has shown that the body chemistry of depressed people is altered in various ways and that deficiencies in neurotransmitters, hormonal imbalances, and other nutritional deficits can contribute to clinical depression. Also, many people with depression do not eat enough, overeat, or eat nonnutritious foods. New research has also connected depression to inflammation and oxidative stress, which are both appropriately managed with nutritional supplements.
St. John’s wort (Hypericum perforatum) is a medicinal herb used for the treatment of neurological and psychiatric disorders, including depression (Nangia M et al 2000). Compared to placebo, H. perforatum extract can effectively treat mild to moderate depression, reducing symptoms and recurrence rate (Lecrubier Y et al 2002).
The mechanism of action of St. John’s wort in depression is not entirely clear. One idea is that St. John’s wort affects presynaptic serotonin uptake and inhibits norepinephrine reuptake (Nangia M et al 2000). By affecting or inhibiting reuptake mechanisms of presynaptic neurons, St. John’s wort may increase availability of serotonin and norephinephrine. Clinical trials show positive response rates to treatment with St. John’s wort (Kim HL et al 1999; Linde K et al 1996).
Life Extension Vacations
Ring in the New Year in Spain, Ireland or Italy!
What better excuse to travel than to say goodbye to the old year and welcome the New Year in an exciting destination.
Enjoy roundtrip airfare, first class accommodations, daily breakfast, sightseeing (per itinerary) in modern air-conditioned motor coach, services of English-speaking tour manager, services of local guides in all major cities, entrance fees (per itinerary), and more.
Additional tour packages are available to make this a most memorable dream come true.
8 Day New Year in Spain from $1779
8 Day New Year in Ireland from $1799
10 Day New Year in Italy from $2969
Life Extension Vacations (Operated by Caribbean Islands Travel)
www.LEVacations.com Phone: 1-800-791-4457
Office operation hours: Mon-Fri 8:30 am to 6:00 pm.