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March 3, 2009
A report published in the March, 2009 issue of the American Journal of Clinical Nutrition described a study conducted by researchers at the University of Adelaide in Australia which found that a combination of testosterone and an oral nutritional supplement may have kept previously undernourished older individuals out of the hospital.
Forty-nine men and women aged sixty-five and older whose nutritional assessment scores categorized them as undernourished were provided with advice on improved dietary intake and were assigned one of the following regimens: oral testosterone undecanoate (80 milligrams twice per day for men and 40 milligrams per day for women), an oral nutritional supplement consisting of 18 percent protein, both testosterone and the nutritional supplement, or no treatment for one year. Participants received regular home visits during which weight, dietary and medication compliance and other factors were assessed.
All participants gained weight by the end of the study. Among those that received the nutritional supplement, grip strength improved. Over the course of the year, 7 men and 6 women had a total of 18 hospital admissions. Four of the admissions occurred among the 12 subjects who received testosterone, 5 occurred in the 13 who received the nutritional supplement, and 9 occurred in the 13 that received no treatment. Among the 11 who received both testosterone and supplemental nutritional therapy, no hospital admissions occurred. Additionally, neither of the two deaths that occurred over the course of the study was among participants who received both treatments.
In their discussion, the authors suggest that testosterone treatment could lower inflammation and stimulate appetite. Proinflammatory cytokines which increase with aging have been shown to inhibit food intake.
"Because hospitalizations are a common and serious event in undernourished older people, this is an exciting finding of considerable potential benefit to many people," the authors conclude. "Larger, confirmatory studies are now needed."
As men age, they begin to experience changes in their bodies. Abdominal fat increases and muscle mass decreases. They also experience a distressing decline in their sex drive. At the same time, the risk of serious health conditions such as depression and heart disease rises. While most conventional physicians (and some members of the lay media) dismiss these woes as signs of “natural aging,” there is often an underlying and identifiable cause of these symptoms—the gradual decline of important sex hormones, especially testosterone.
Too often, men who have problems related to a low testosterone level are advised to treat only the symptoms of their conditions (such as taking antidepressant and/or cholesterol-lowering drugs). Fortunately, progressive physicians, along with the Life Extension Foundation, now recognize the connection between hormones and the diseases of aging. Restoration of youthful hormone levels is associated with optimal sexual function, energy, and vitality, while declining hormone levels correlate with many age-related conditions, including high blood pressure, atherosclerosis, diabetes, loss of muscle and bone mass, and fatigue (Shores MM et al 2004).
Bone integrity depends upon a balance between bone formation and bone resorption, which are controlled by multiple factors including estrogen and testosterone (Rucker D et al 2004; Tok EC et al 2004; Valimaki VV et al 2004). One clinical trial has demonstrated that testosterone increases bone mineral density in elderly men (van den Beld AW et al 2000). Testosterone supplementation also has a positive effect on muscle metabolism and strength (Herbst KL et al 2004).
Life Extension Vacations
Rancho La Puerta
Reenergize your body by surrounding yourself with nature’s beauty…
Located on the Baja Peninsula, in Tecate, Mexico, just forty miles southeast of San Diego, the Ranch is recognized as the first and oldest fitness destination spa in North America. With 3,000-acre of natural beauty Rancho La Puerta offers world-class gardens, an organic farm, and mountainsides of scenic vistas and meadows for great hiking and walking experiences.
Seven nights (Saturday to Saturday) from $2795* per person
Rates include accommodations, organic meals, great fitness classes, guided hikes in beautiful mountains, evening programs, outstanding guest speakers, use of all facilities and scheduled transportation to and from San Diego International Airport.
Exclusive for Life Extension members:
Book a 7-night package and receive a “Piñata Plan” which includes 5 complimentary spa therapies**
Ask about our special rates for singles and partial-week packages!
- * Rates are per person based on double occupancy. Guests arrive on a Saturday and depart on the following Saturday. Mexican room tax (approx. 7%) is additional.
** Choose from any therapies that last 50 minutes or less
- Call Life Extension Vacations toll-free at 1-800-791-4457
- Mon-Fri 8:30 am – 6:00 pm ET.
- Email: firstname.lastname@example.org
- More details: www.LEVacations.com
Blueberry Extract with Pomegranate & CocoaGold™
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When scientists analyze fruits and vegetables for their antioxidant capability, blueberries rank among the highest in their capacity to destroy free radicals. Rich in antioxidants that combat oxidative stress, blueberry extracts not only help preserve youthful cognitive function, but also help maintain healthy blood flow via several mechanisms, including maintaining already normal LDL levels and endothelial function.
To augment the benefits of this healthful fruit, a new wild blueberry extract has been added to Blueberry Extract with Pomegranate and CocoaGold™ that provides more potent active ingredients than cultivated blueberries. Blueberry Extract with Pomegranate and Cocoa-Gold™ now contains AuroraBlue®, which contains the only true wild Alaskan blueberries that grow in a completely natural environment without exposure to any chemicals. This complex of wild fruits belonging to the genus Vaccinium is rich in unique antioxidants (anthocyanins and pterostilbene being the two most active) and possesses nearly 10 times the antioxidant capacity of cultivated berries.
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Due to overwhelming scientific evidence demonstrating the unique health benefits of the polyphenols found in pomegranate fruit, Life Extension has added standardized pomegranate extract to Life Extension Mix (tablets, capsules, powder) and Blueberry Extract Capsules. For those who desire higher doses, a stand-alone Pomegranate Extract and Pomegranate Juice Concentrate have also been formulated.
When we drink coffee or other quick-release caffeine beverages, there is a surge of noradrenaline release in the brain that gives us a burst of energy. The problem is that this sudden release of noradrenaline depletes its precursor, L-phenylalanine, thereby causing the caffeine “letdown” effect so many people experience later in the day. By taking L-phenylalanine and other noradrenaline factors with caffeine, many people are able to achieve sustained energy levels throughout the day. The reason is that the L-phenylalanine induces more noradrenaline to be produced in the brain.
Blast™ is a high-performance designer food comprised of caffeine, L-phenylalanine (an essential nutrient amino acid), and essential nutrient cofactors. Use Blast™ for a fast start to a long, hard-driving day of work or play. The product includes a flavor system comprised of citric acid, malic acid, fumaric acid (the substances that give many fruits such as apples, oranges, and cherries their tart flavor), natural flavors, and silicon dioxide (mineral dispersant and wetting agent).