A report in the June, 2012 issue of Nutrition Research revealed the results of a double-blinded trial which found a benefit for supplementation with green tea extract on blood pressure, inflammation, oxidative stress and insulin resistance. "To the best of our knowledge, this is the first clinical trial performed on obese, hypertensive patients," announce authors Pawel Bogdanski and his colleagues at Poland's Poznan University.
Fifty-six men and women with high blood pressure and a body mass index of 30 kg/m2 or more were randomized to receive a capsule containing 379 milligrams green tea extract or a placebo for three months. Blood pressure and serum levels of lipids, glucose, antioxidants, insulin and the inflammatory markers tumor necrosis factor alpha (TNF-a) and C-reactive protein (CRP) were measured before and after treatment.
At the end of the study, subjects who received green tea had improved insulin resistance, blood pressure, lipids, inflammation and total antioxidant status. Dr Bogdanski and his associates remark that green tea's anti-inflammatory and antioxidant actions may explain its cardioprotective and blood pressure-lowering effects.
"The present findings demonstrate strong evidence for a beneficial influence of green tea extract supplementation on blood pressure, carbohydrate metabolism, and lipid profile, as well as on inflammation and oxidative stress, in patients with obesity-related hypertension," the authors write. "Further studies on a larger scale and with a longer duration of observation are needed to support our data and to explore their mechanistic basis."
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