Whole Body Health Sale

Life Extension Update

Heart attack risk lower among women with high anthocyanin intake

Heart attack risk lower among women with high anthocyanin intake

Friday, January 18, 2013. The January 15, 2013 issue of Circulation: Journal of the American Heart Association reported the finding of a decrease in the risk of myocardial infarction in women with a high intake of anthocyanins—flavonoids that occur in significant amounts in such plant foods as blueberries and strawberries. "We have shown that even at an early age, eating more of these fruits may reduce risk of a heart attack later in life," remarked lead author Aedín Cassidy, PhD, who heads the Department of Nutrition at Norwich Medical School of the University of East Anglia in England.

The study included 93,600 women between the ages of 25 to 42 upon enrollment in the Nurses' Health Study II in 1989. Dietary questionnaires completed every four years beginning in 1991 provided information on the intake of anthocyanins, which include cyanidin, delphinidin, malvidin, pelargonidin, petunidin and peonidin. The participants were followed for 18 years, during which 405 heart attacks occurred.

Anthocyanin intake ranged from 2 to 35 milligrams per day. Among women whose intake of anthocyanins was among the top one-fifth of subjects, there was a 32 percent lower risk of heart attack in comparison with those whose intake was among the lowest fifth, and when those in the top one-tenth were compared with the lowest tenth, the risk was 47 percent lower. For each 15 milligram daily increase in anthocyanin intake, myocardial infarction risk was lowered by 17 percent.

When the researchers analyzed the intake of dietary sources of anthocyanin (blueberries and strawberries), participants who consumed at least three servings per week had a 34 percent lower heart attack risk compared to those who seldom consumed them. Onions consumed at least five times per week were also protective.

"Our findings suggest that bioactive compounds present in red and blue fruits and vegetables commonly consumed in the habitual diet may be associated with a reduced risk of myocardial infarction in young and middle-aged women," the authors conclude. " Further prospective studies, including studies with biomarkers of coronary heart disease risk to elucidate mechanisms, are needed to confirm these associations. Randomized trials focusing on commonly consumed anthocyanin-rich foods are also needed to examine dose-response effects and to be of long-enough duration to assess clinically relevant end points."

"Blueberries and strawberries can easily be incorporated into what women eat every week," noted senior author Eric Rimm, ScD, who is an Associate Professor of Nutrition and Epidemiology at the Harvard School of Public Health. "This simple dietary change could have a significant impact on prevention efforts."

shadow
What's Hot Highlight

Higher dietary antioxidant capacity associated with lower cardiovascular disease indicators

What's Hot

In an article published online on January 4, 2013 in the European Journal of Clinical Nutrition, researchers from the University of Connecticut report an association between improved dietary antioxidant capacity and reductions in plasma homocysteine and C-reactive protein (CRP), both of which are markers of increased cardiovascular disease risk.

The study included 4,391 men and women who participated in the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Questionnaire responses concerning diet and supplement use over a 24 hour period were analyzed to provide the antioxidant capacities of 43 nutrients. (The antioxidant capacity of 30 flavonoids was determined from food sources only.) Blood samples were analyzed for serum levels of alpha and gamma tocopherols, six carotenoids and CRP, and plasma total homocysteine.

Total antioxidant capacity (TAC) was correlated with serum vitamin E and carotenoid levels. As TAC rose, the risk of having a total homocysteine level of greater than 13 micromoles per liter decreased. Those whose intake of antioxidants was among the top 25 percent of participants had more than double the chance of having a homocysteine level under 13 micromoles per liter in comparison with those whose TAC was among the lowest fourth. A reduction in the risk of having a CRP level of 3 milligrams per liter or higher was also observed in association with increasing TAC. A significant decline in homocysteine and CRP was observed in association with higher TAC from diet combined with supplements or supplements alone, but not with diet alone.

"Dietary TAC was associated with improved serum antioxidant status and decreased risk factors of cardiovascular disease including serum CRP and plasma total homocysteine concentrations," the authors conclude. "The implicated applicability of dietary TAC needs further validation in prospective cohort studies."

Super Sale: Save More Than Money!

Annual Super Sale on Now!

Get these breakthrough products to help you stay younger and healthier longer. Stock up on all the health essentials you need all year. Below are just a few examples of the significant savings available during this year's Super Sale:

Super Ubiquinol CoQ10 with Enhanced Mitochondrial Support™, 100 mg, 60 softgels
Item #01426

$62.00
$35.10*

Super Omega-3 EPA/DHA with Sesame Lignans & Olive Fruit Extract, 120 softgels
Item #01482

$32.00
$16.81*

Life Extension Mix™ Capsules, 490 capsules
Item #01754

$110.00
$57.38*

Bone Restore with Vitamin K2, 150 capsules
Item #01711

$26.00
$15.53*

Vitamin D3, 5000 IU, 60 softgels
Item #01713

$11.00
$6.68*

Cognitex® with NeuroProtection Complex, 90 softgels
Item #01696

$72.00
$38.45*

*Price based on super sale member volume purchase.


http://www.lef.org/SuperSale/

Super Sale: Save Far More Than Money

Latest Supplements

Optimized Quercetin

The Fatigue Solution, by Eva Cwynar MD with Sharon Kolberg
Item #33847

add to cart

Too often, uninformed physicians diagnose fatigue, difficulty concentrating, unwanted weight gain, and hair loss in their patients as the inevitable results of aging. This blanket diagnosis may be flat out wrong. In fact, your lack of energy and inability to focus may have nothing at all to do with your age. You may simply need to adjust a thyroid malfunction. The thyroid affects every cell in your body and is a key regulator of your energy, metabolism, heart, and bones. In her new book, The Fatigue Solution, Eva Cwynar, MD, urges readers to have their thyroid checked with a simple blood test.

The Fatigue Solution will show you how you can go from fatigued to fabulous by following eight simple steps. It is a 21st century woman's health guide for generating physical as well as emotional strength, balancing hormones, reclaiming sexual vitality, and restoring energy.

Kyolic® Garlic Formula 102

Reishi Extract Mushroom Complex, 60 vegetarian capsules
Item #01708

add to cart

An abundance of evidence demonstrates that Reishi constituents enhance the protective activity of the body's hematopoietic stem cells, T-cells, and other crucial immune factors. Reishi's immune-supporting compounds include an array of unique polysaccharides, triterpenes, and other constituents, many of which assist activation of the cell surface receptors that modulate normal immunity.

The Reishi mushroom also supports the body's production of endogenous antioxidant enzymes—such as superoxide dismutase (SOD), catalase, and glutathione—which, in turn, support the body's natural immune defenses against free radical damage.

Reishi Extract Mushroom Complex delivers powerful compounds and represents the next generation of natural immune support.

shadow

Highlight

Life Extension Update What's Hot
Blueberries protect against cardiovascular disease risk factors in metabolic syndrome patients Increased flavonoid consumption associated with reduced cardiovascular deaths
Two new articles confirm numerous cardiovascular benefits for grape polyphenols Berries benefit blood pressure
Greater intake of some flavonoids linked with reduced cardiovascular and all cause mortality among women over a 16 year period Flavonoids lower chronic disease risk
       
Life Extension Magazine® Health Topics
Broad-spectrum disease defense with novel berry extract Atherosclerosis and cardiovascular disease
The disease-fighting power of berries High blood pressure
Antioxidant power blueberries and bilberries slow brain aging and protect vision    
       

shadow