Whole Body Health Sale

Life Extension Update

Stroke risk lower in coffee and tea drinkers

Stroke risk lower in coffee and tea drinkers

Tuesday, March 19, 2013. An article published on March 14, 2013 in Stroke: Journal of the American Heart Association reveals a protective effect for green tea and coffee against stroke in middle-aged men and women.

Yoshiro Kokubo, MD, PhD and associates analyzed data from 82,369 participants who were free of cancer or heart disease upon enrollment in the Japan Public Health Center-Based Study Cohort I and II. Dietary questionnaires administered at enrollment provided information on green tea and coffee consumption frequency. The subjects were followed for an average of 13 years, during which 3,425 strokes (including 1,964 cerebral infarctions, 1,001 intracerebral hemorrhages and 460 subarachnoid hemorrhages) and 910 coronary heart disease events occurred, resulting in a total of 4,335 cardiovascular disease events.

In comparison with those whose tea drinking was categorized as seldom at less than once per month, drinking two to three cups green tea per day was associated with a 14% lower risk of stroke and drinking more than four cups per day with a 20% reduction. Among coffee consumers, drinking the beverage three to six times per week was associated with an 11% lower risk and consuming it once per day was associated with a 20% decrease compared to seldom drinkers. The risk was particularly significant for intracerebral hemorrhage, for which the adjusted risk was reduced by 35 percent among those who consumed at least four cups green tea per day. While total cardiovascular events were lower in association with increased tea or coffee intake, no significant association was observed for coronary heart disease.

"This is the first large-scale study to examine the combined effects of both green tea and coffee on stroke risks," announced Dr Kokubo who is affiliated with the Department of Preventive Cardiology at Japan's National Cerebral and Cardiovascular Center. "You may make a small but positive lifestyle change to help lower the risk of stroke by adding daily green tea to your diet."

"The regular action of drinking tea, coffee, largely benefits cardiovascular health because it partly keeps blood clots from forming," he noted.

Other possible mechanisms cited by the authors include the ability of compounds found in tea to protect against oxidative stress and inflammation and for those in coffee to improve blood glucose levels.

shadow
What's Hot Highlight

Omega-3 emulsion reduces stroke damage

What's Hot

On February 20, 2013 in the journal PLOS One, Columbia University researchers report a benefit for omega-3 fatty acid-rich triglyceride lipid emulsions in an experimental model of ischemic stroke.

Richard J. Deckelbaum and his associates induced stroke in ten-day old mice and exposed them to a low oxygen environment for 15 minutes. Groups of animals were intraperitoneally injected with triglyceride emulsions containing the omega-3 fatty acids EPA, DHA or both omega-3 acids; omega-6-rich triglyceride emulsions or saline before and/or after brain injury was induced. Twenty-four hours subsequent to blood flow restoration, the animals' brains were examined for damage.

Treatment with EPA and DHA prior to brain injury reduced total infarct volume by an average of 43 percent, and by 47 percent when the fatty acids were given afterward. A triglyceride emulsion enriched with DHA alone was found to reduce infarct volume by 51 percent when administered immediately after injury as well as when given two hours later. Examination of brain tissue from mice that received DHA revealed that the benefit was maintained after eight weeks.

"Since mice have a much faster metabolism than humans, longer windows of time for therapeutic effect after stroke are likely in humans," Dr Deckelbaum commented.

"A number of pathways are likely involved in omega-3 triglyceride neuroprotection," the authors write. "For example, chronic administration of DHA resulted in increases of DHA levels in brain mitochondria."

They add that DHA could help inhibit programmed cell death and improve the mitochondria's ability to handle excessive intracellular calcium resulting from ischemia. "In most clinical trials in the past, the compounds tested affected only one pathway," Dr Deckelbaum noted. "Omega-3 fatty acids, in contrast, are very bioactive molecules that target multiple mechanisms involved in brain death after stroke."

Free Webinar

Safely restore youthful hormone levels

Hosted by Michael A. Smith, M.D.

Wednesday, March 27, 2013 7 pm-8 pm ET

Please join Life Extension®'s webinar highlighting scientifically proven methods for safely restoring youthful hormone levels. Hormones are the juice of life and without them we age fast and develop age-related diseases. Dr. Mike will discuss ways that you can increase hormone levels while retaining proper balance. Don't miss this exciting lecture presented by the "country doctor with a city education."

Register Now
Reserve your webinar seat now at: https://www2.gotomeeting.com/
register/803725242

After registering, you will receive a confirmation e-mail containing information about joining the webinar.

System Requirements

PC-based attendees
Required: Windows® 7, Vista, XP or 2003 Server

Macintosh®-based attendees
Required: Mac OS® X 10.5 or newer

Mobile attendees
Required: iPhone®, iPad®, Android™ phone or Android Tablet

Visit www.lef.org/media to view past webinars!

Latest Supplements

Super Carnosine, 500 mg, 90 vegetarian capsules
Item #01687

add to cart

Carnosine is a multifunctional dipeptide made up of the amino acids beta-alanine and L-histidine. It is found both in food and in the human body. Long-lived cells such as nerve cells (neurons) and muscle cells (myocytes) contain high levels of carnosine. Muscle levels of carnosine correlate with the maximum life spans of animals. Carnosine has a number of antioxidant properties and has been shown to be an antiglycating agent.

This nutrient has the ability to suppress formation of advanced glycation end products (AGEs) and inhibit the formation of reactive oxygen species (ROS), a culprit in oxidative stress that can lead to age-related conditions. Carnosine levels decline with age. Muscle levels decline 63% from age 10 to age 70, which may account for the normal age-related decline in muscle mass and function.

Since carnosine acts as a pH buffer, it can keep on protecting muscle cell membranes from oxidation under the acidic conditions of muscular exertion. Carnosine enables the heart muscle to contract more efficiently through enhancement of calcium response in heart myocytes.

Kyolic® Garlic Formula 102

MSM (Methylsulfonylmethane), 1000 mg, 100 capsules
Item #00451

add to cart

As people age, systemic inflammation can inflict degenerative effects throughout the body. A primary cause of this destructive cascade is the production of cell-signaling chemicals known as pro-inflammatory cytokines. Along with these dangerous cytokines, imbalances of hormone-like messengers called prostaglandins and leukotrienes also contribute to inflammatory processes.

MSM (methylsulfonylmethane or dimethylsulfone) is a sulfur-containing molecule found in various plants and some body tissues. MSM is a vital building block of joints, cartilage, skin, hair and nails. It is a natural and efficient source of the sulfur that is used by many of the body's structural molecules. Peer-reviewed clinical research in the U.S. has shown MSM is safe and effective in increasing joint comfort and supporting a normal range of motion.

shadow

Highlight

Life Extension Update What's Hot
Study finds coffee drinkers have fewer strokes Tea drinking associated with fewer heart disease deaths over 13 year period
Meta-analysis finds lower risk of stroke among tea drinkers Tea extract lowers cholesterol
Green tea helps prevent stroke-induced brain damage Tannins from green tea and other plants protect against stroke damage
Life Extension Magazine® Health Topics
National institutes of health discovers protective effects of coffee Stroke
Discovering coffee's unique health benefits Atherosclerosis and cardiovascular disease
Green tea: good for the soul-but even better, good for the heart Blood clot prevention

shadow