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Summary

The drugs, hormones, and nutrients discussed in this protocol have documented mechanisms of action that may benefit the cancer patient. The objective of implementing an adjuvant regimen consisting of multiple agents is to increase the odds of achieving a long remission. Once a remission is achieved, preventing recurrence and secondary cancers becomes a lifetime commitment.

Few oncologists aggressively seek to prevent recurrence once the primary disease appears to have been eradicated. However, the regrettable facts are that colonies of cancer cells can remain dormant in the body for years or decades before reappearing as full-blown disease that is highly resistant to treatment. This has been documented in autopsy studies of people who died of diseases other than cancer but nonetheless showed significant residual metastatic tumors in their bodies.

Nutrient

Preventive Dose

Cancer Adjuvant Dose

Apigenin

10 – 25 mg daily

20 – 50 mg daily

Astaxanthin

2 – 4 mg daily

6 – 12 mg daily

Astragalus

500 mg daily

2000 – 4000 mg daily

Blueberry

180 – 450 mg daily

900 – 1800 mg daily

Chrysin

500 mg daily

1000-2000 mg daily

Curcumin

400 mg daily of a  BCM-95® extract with food

800-3600 mg daily of a BCM-95® extract with food

Coenzyme Q10

100 mg daily with food

200-400 mg daily with food

Green Coffee Extract (standardized to 50% chlorogenic acid)

400 mg three times daily, before meals

400 mg three times daily, before meals

EPA-DHA fatty acids

2000 – 4000 mg daily of fish oil concentrate supplying 700 – 1400 mg EPA and 500 – 1000mg DHA with food

4000 – 8000 mg daily of fish oil concentrate supplying up to 2800 mg EPA and 2000 mg DHA with food

Garlic

600 mg daily with food

1200 – 4800 mg daily with food

Gamma Tocopherol

200 – 250 mg daily with food

400 – 1000 mg daily with food

GLA (gamma-linolenic acid)

300 mg daily with food

700 – 900 mg daily with food

Grape Seed Extract

100 mg daily

300 mg daily

Green Tea Extract 

300 – 350 mg daily of EGCG

Up to 3000 mg daily of EGCG

Cruciferous vegetable concentrate

1 tbsp daily

1 – 4 tbsp daily

Indole 3 Carbinol (I3C)

80 – 160 mg daily

200 – 600 mg daily

Lignans

25 – 50 mg daily

75 – 125 mg daily

Lipoic acid (Sodium R-lipoate)

240 – 480 mg daily on an empty stomach

600 – 1200 mg daily on an empty stomach

Lycopene

10 mg daily with food

15 – 45 mg daily with food

Melatonin

300 mcg-3 mg before bed

10 – 50 mg between 8 – 10pm

Panax ginseng

100 mg daily of standardized to contain 4-7% ginsenosides

200 – 600 mg daily of standardized to contain 4-7% ginsenosides

Pomegranate

80 – 120 mg daily of punicalagins

280 – 375 mg daily of punicalagins

Proteolytic Enzymes

1 – 2 pills daily on an empty stomach of a formula containing pancreatin, papain, trypsin, and chymotrypsin

2 – 10 pills, 3 times daily on an empty stomach of a formula containing pancreatin, papain, trypsin, and chymotrypsin

PSK (Coriolus versicolor)

600 – 1200 mg daily of a 40% polysaccharide extract

3000 mg daily of a 40% polysaccharide extract

Pterostilbene

0.25-3 mg daily

1 – 3 mg daily

Quercetin

500 mg daily

1000 – 3000 mg daily

Reishi

980 mg daily of standardized to contain 13.5% polysaccharides and 6% triterpenes

980 – 3000 mg daily of standardized to contain 13.5% polysaccharides and 6% triterpenes

Selenium

200 mcg daily with food

200 – 600 mcg daily with food

Silibinin

225 mg daily

225 – 450 mg daily

Sulforaphane

400 – 800 mg daily (broccoli extract)

400 – 1600 mg daily (broccoli extract)

Vitamin C

1000 – 3000 mg daily

4 – 12 g daily

Vitamin D3

2000 – 10 000 IU daily with food, based on individual blood testing. Optimal blood levels of vitamin D are 50 – 80 ng/ml.

2000 – 10 000 IU daily with food, based on individual blood testing. Optimal blood levels of vitamin D are 50 – 80 ng/ml.

In too many cases, a breast, melanoma, or other cancer reemerges that was supposed to have been cured. Scientists speculate that the body has natural anticancer control mechanisms that may diminish with age and exposure to physical and emotional stress factors. It is thus important for cancer patients to be vigilant in maintaining an inhospitable environment for cancer cells to propagate and protecting against age-associated immune dysfunction.

We have prepared the chart above to summarize recommendations on the basic dietary supplements and suggested doses for cancer prevention and adjuvant treatment. In addition to the agents listed here, a number of other potential adjuvant approaches are discussed in this protocol. For long-term control of cancer, some cancer patients attempt to incorporate as many of these adjuvant approaches as are tolerable and affordable. Others pick and choose which drugs, hormones, and supplements they want to consume over the long term.

Patients should read the other cancer protocols in this book, with special attention given to Cancer: Should Patients Take Dietary Supplements? and Cancer Treatment: The Critical Factors. If surgery, radiation, or chemotherapy is being considered, please refer to these specific protocols: Cancer Surgery, Cancer Radiation, and Cancer Chemotherapy.

Note: While it would be wholly inappropriate for the Life Extension Foundation to steer individuals in decisions of omission or commission regarding therapies, it would be equally improper to shun responsibility. Because we are challenged by a professional and moral commitment to assist in overcoming appalling statistics, we have discussed some controversial issues in this protocol. We look forward to new findings to better substantiate optimal therapeutic approaches.