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Leukemia
Updated: 01/25/2006

References

Aggarwal BB, Bhardwaj A. et al. Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res . 2004 Sep;24(5A):2783-840.

Aggarwal BB, Kumar A. et al. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res . 2003 Jan;23(1A):363-98.

Aguayo A, Kantarjian H. et al. Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes. Blood . 2000 Sep 15;96(6):2240-5.

Ahmed N, Laverick L. et al. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells. Anticancer Res . 2001 Sep;21(5):3519-23.

Alter BP. Cancer in Fanconi anemia, 1927-2001. Cancer . 2003 Jan 15;97(2):425-40.

Ames BN. Cancer prevention and diet: help from single nucleotide polymorphisms. Proc Natl Acad Sci U S A . 1999 Oct 26;96(22):12216-8.

Ames BN. Micronutrients prevent cancer and delay aging. Toxicol Lett . 1998 Dec 28;102-103:5-18.

Ames BN, Shigenaga MK. et al. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A . 1993 Sep 1;90(17):7915-22.

Anders O, Nagel HR. et al. [Blood coagulation factors and proteinase inhibitors in cytostatic therapy of acute leukemia]. Folia Haematol Int Mag Klin Morphol Blutforsch . 1988;115(5):769-80.

Anderson GD, Rosito G. et al. Drug interaction potential of soy extract and Panax ginseng. J Clin Pharmacol . 2003 Jun;43(6):643-8.

Arbiser JL, Klauber N. et al. Curcumin is an in vivo inhibitor of angiogenesis. Mol Med . 1998 Jun;4(6):376-83.

Archer VE. Association of nuclear fallout with leukemia in the United States. Arch Environ Health . 1987 Sep;42(5):263-71.

Asou H, Koshizuka K. et al. Resveratrol, a natural product derived from grapes, is a new inducer of differentiation in human myeloid leukemias. Int J Hematol . 2002 Jun;75(5):528-33.

Austin H, Delzell E. et al. Benzene and leukemia. A review of the literature and a risk assessment. Am J Epidemiol . 1988 Mar;127(3):419-39.

Balaian L, Ball ED. Inhibition of acute myeloid leukemia cell growth by mono-specific and bi-specific anti-CD33 x anti-CD64 antibodies. Leuk Res . 2004 Aug;28(8):821-9.

Baroni S, Scribano D. et al. Lipids and lipoproteins in acute lymphoblastic leukaemia (ALL). Leuk Res . 1994 Aug;18(8):643-4.

Baroni S, Scribano D. et al. Prognostic relevance of lipoprotein cholesterol levels in acute lymphocytic and nonlymphocytic leukemia. Acta Haematol . 1996;96(1):24-8.

Barton JC, Poon MC. Coagulation testing of Hickman catheter blood in patients with acute leukemia. Arch Intern Med . 1986 Nov;146(11):2165-9.

Bessmel'tsev SS, Abdulkadyrov KM. [The importance of sonography in the diagnosis of extramedullary hematopoietic foci in acute leukemia]. Vopr Onkol . 1991;37(11-12):1054-62.

Bhatia N, Agarwal R. Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. Prostate . 2001 Feb 1;46(2):98-107.

Bieker R, Padro T. et al. Overexpression of basic fibroblast growth factor and autocrine stimulation in acute myeloid leukemia. Cancer Res . 2003 Nov 1;63(21):7241-6.

Biganzoli L, Untch M. et al. Neulasta (pegfilgrastim): a once-per-cycle option for the management of chemotherapy-induced neutropenia. Semin Oncol . 2004 Jun;31(3 Suppl 8):27-34.

Bischof O, Kim SH. et al. Regulation and localization of the Bloom syndrome protein in response to DNA damage. J Cell Biol . 2001 Apr 16;153(2):367-80.

BROHULT A. Effects of alkoxyglycerols and especially selachyl alcohol on the bone marrow in connexion with irradiation treatment and in leukaemia therapy. Nature . 1958 May 24;181(4621):1484-5.

Buckley R, Shewring B. et al. Circulating triacylglycerol and apoE levels in response to EPA and docosahexaenoic acid supplementation in adult human subjects. Br J Nutr . 2004 Sep;92(3):477-83.

Call TG, Noel P. et al. Incidence of leukemia in Olmsted County, Minnesota, 1975 through 1989. Mayo Clin Proc . 1994 Apr;69(4):315-22.

Carlo-Stella C, Dotti G. et al. Selection of myeloid progenitors lacking BCR/ABL mRNA in chronic myelogenous leukemia patients after in vitro treatment with the tyrosine kinase inhibitor genistein. Blood . 1996 Oct 15a;88(8):3091-100.

Carlo-Stella C, Regazzi E. et al. Effect of the protein tyrosine kinase inhibitor genistein on normal and leukaemic haemopoietic progenitor cells. Br J Haematol . 1996 Junb;93(3):551-7.

Cartwright RA, Gurney KA. et al. Sex ratios and the risks of haematological malignancies. Br J Haematol . 2002 Sep;118(4):1071-7.

Castello L, Tessitore L. Reservatol inhibits cell cycle progression in U937 cells. Oncol Rep . 2005 Jan;13(1):133-7.

Catalina F, Milewich L. et al. Dietary dehydroepiandrosterone inhibits bone marrow and leukemia cell transplants: role of food restriction. Exp Biol Med (Maywood ) . 2003 Dec;228(11):1303-20.

Cervetti G, Galimberti S. et al. Rituximab as treatment for minimal residual disease in hairy cell leukaemia. Eur J Haematol . 2004 Dec;73(6):412-7.

Chatta GS, Dale DC. Aging and haemopoiesis. Implications for treatment with haemopoietic growth factors. Drugs Aging . 1996 Jul;9(1):37-47.

Cohen IJ. Defining the appropriate dosage of folinic acid after high-dose methotrexate for childhood acute lymphatic leukemia that will prevent neurotoxicity without rescuing malignant cells in the central nervous system. J Pediatr Hematol Oncol . 2004 Mar;26(3):156-63.

Cohen L, de MC. et al. Endocrine levels at the start of treatment are associated with subsequent psychological adjustment in cancer patients with metastatic disease. Psychosom Med . 2001 Nov;63(6):951-8.

Conti A, Haran-Ghera N. et al. Role of pineal melatonin and melatonin-induced-immuno-opioids in murine leukemogenesis. Med Oncol Tumor Pharmacother . 1992;9(2):87-92.

Dale DC. Colony-stimulating factors for the management of neutropenia in cancer patients. Drugs . 2002;62 Suppl 1:1-15.

De CR, Liao JK. et al. Fatty acid modulation of endothelial activation. Am J Clin Nutr . 2000 Jan;71(1 Suppl):213S-23S.

Defacque H, Commes T. et al. Expression of Retinoid X Receptor alpha is increased upon monocytic cell differentiation. Biochem Biophys Res Commun . 1996 Mar 18;220(2):315-22.

El-Sokkary GH, Reiter RJ. et al. Melatonin supplementation restores cellular proliferation and DNA synthesis in the splenic and thymic lymphocytes of old rats. Neuro Endocrinol Lett . 2003 Jun;24(3-4):215-23.

Elstner E, Linker-Israeli M. et al. Combination of a potent 20-epi-vitamin D3 analogue (KH 1060) with 9-cis-retinoic acid irreversibly inhibits clonal growth, decreases bcl-2 expression, and induces apoptosis in HL-60 leukemic cells. Cancer Res . 1996 Aug 1;56(15):3570-6.

Esposito D, Fassina G. et al. Chromosomes of older humans are more prone to aminopterine-induced breakage. Proc Natl Acad Sci U S A . 1989 Feb;86(4):1302-6.

Estrov Z, Shishodia S. et al. Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells. Blood . 2003 Aug 1;102(3):987-95.

Eubank TD, Roberts R. et al. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice. Immunity . 2004 Dec;21(6):831-42.

Everaus H. Hormones and immune responsiveness in chronic lymphocytic leukemia. Leuk Lymphoma . 1992 Dec;8(6):483-9.

Everaus H, Luik E. et al. Active and indolent chronic lymphocytic leukaemia--immune and hormonal peculiarities. Cancer Immunol Immunother . 1997 Oct;45(2):109-14.

Fayad L, Keating MJ. et al. Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: correlation with phenotypic characteristics and outcome. Blood . 2001 Jan 1;97(1):256-63.

Featherstone C, Delaney G. et al. Estimating the optimal utilization rates of radiotherapy for hematologic malignancies from a review of the evidence. Cancer . 2005 Jan 15;103(2):393-401.

Feldman EJ. Monoclonal antibody therapy in acute myeloid leukemia. Curr Hematol Rep . 2003 Jan;2(1):73-7.

Felix CA. Secondary leukemias induced by topoisomerase-targeted drugs. Biochim Biophys Acta . 1998 Oct 1;1400(1-3):233-55.

Fenech MF, Dreosti IE. et al. Folate, vitamin B12, homocysteine status and chromosome damage rate in lymphocytes of older men. Carcinogenesis . 1997 Jul;18(7):1329-36.

Fernandez C, Lobo Md Mdel V. et al. Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. Exp Cell Res . 2004 Oct 15;300(1):109-20.

Ferrajoli A, Manshouri T. et al. High levels of vascular endothelial growth factor receptor-2 correlate with shortened survival in chronic lymphocytic leukemia. Clin Cancer Res . 2001 Apr;7(4):795-9.

Fiorenza AM, Branchi A. et al. Serum lipoprotein profile in patients with cancer. A comparison with non-cancer subjects. Int J Clin Lab Res . 2000;30(3):141-5.

Fong CT, Brodeur GM. Down's syndrome and leukemia: epidemiology, genetics, cytogenetics and mechanisms of leukemogenesis. Cancer Genet Cytogenet . 1987 Sep;28(1):55-76.

Gajate C, An F. et al. Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/. Clin Cancer Res . 2003 Apr;9(4):1535-45.

Gao X, Xu YX. et al. Disparate in vitro and in vivo antileukemic effects of resveratrol, a natural polyphenolic compound found in grapes. J Nutr . 2002 Jul;132(7):2076-81.

Gescher A. Polyphenolic phytochemicals versus non-steroidal anti-inflammatory drugs: which are better cancer chemopreventive agents? J Chemother . 2004 Nov;16 Suppl 4:3-6.

Gillis RC, Daley BJ. et al. Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. J Surg Res . 2002 Sep;107(1):145-53.

Gonin JM, Nguyen H. et al. Controlled trials of very high dose folic acid, vitamins B12 and B6, intravenous folinic acid and serine for treatment of hyperhomocysteinemia in ESRD. J Nephrol . 2003 Jul;16(4):522-34.

Granzotto M, Rapozzi V. et al. Effects of melatonin on doxorubicin cytotoxicity in sensitive and pleiotropically resistant tumor cells. J Pineal Res . 2001 Oct;31(3):206-13.

Greaves MF. Biological models for leukaemia and lymphoma. IARC Sci Publ . 2004;(157):351-72.

Guilhot F, Roy L. et al. Interferon therapy in chronic myelogenous leukemia. Hematol Oncol Clin North Am . 2004 Jun;18(3):585-603, viii.

Hagen TM, Ingersoll RT. et al. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. FASEB J . 1999 Feb;13(2):411-8.

Haimov I, Lavie P. Melatonin - a chronobiotic and soporific hormone. Arch Gerontol Geriatr . 1997 Mar;24(2):167-73.

Harries M, O'Donnell A. et al. Phase I/II study of DHA-paclitaxel in combination with carboplatin in patients with advanced malignant solid tumours. Br J Cancer . 2004 Nov 1;91(9):1651-5.

Hassan HT. Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy. Leuk Res . 2004 Jul;28(7):667-71.

Hawkins MM. Secondary leukaemia after epipodophyllotoxins. Lancet . 1991 Nov 30;338(8779):1408.

Higuchi T, Shimizu T. et al. Coagulation patterns of disseminated intravascular coagulation in acute promyelocytic leukemia. Hematol Oncol . 1997 Nov;15(4):209-17.

Huang ME, Ye YC. et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood . 1988 Aug;72(2):567-72.

Huppert FA, Van Niekerk JK. Dehydroepiandrosterone (DHEA) supplementation for cognitive function. Cochrane Database Syst Rev . 2001;(2):CD000304.

Hurley MM, Marcello K. et al. Signal transduction by basic fibroblast growth factor in rat osteoblastic Py1a cells. J Bone Miner Res . 1996 Sep;11(9):1256-63.

Ichimaru M, Tomonaga M. et al. Atomic bomb and leukemia. J Radiat Res (Tokyo) . 1991 Dec;32 Suppl 2:14-9.

Inserra P, Zhang Z. et al. Modulation of cytokine production by dehydroepiandrosterone (DHEA) plus melatonin (MLT) supplementation of old mice. Proc Soc Exp Biol Med . 1998 May;218(1):76-82.

Irons RD, Stillman WS. The process of leukemogenesis. Environ Health Perspect . 1996 Dec;104 Suppl 6:1239-46.

Isidori A, Bonifazi F. et al. Autologous stem cell transplantation for acute myeloid leukemia patients in first complete remission: a 10-year follow-up study of 118 patients. Haematologica . 2005 Jan;90(1):139-41.

Itala M, Pelliniemi TT. et al. Long-term treatment with GM-CSF in patients with chronic lymphocytic leukemia and recurrent neutropenic infections. Leuk Lymphoma . 1998 Dec;32(1-2):165-74.

Jee SH, Shen SC. et al. Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells. J Invest Dermatol . 1998 Oct;111(4):656-61.

Jenkins MY, Mitchell GV. et al. Dietary vitamin E and beta-carotene sources influence vitamin A and E storage in young rats fed marginal and adequate vitamin E. Nutr Cancer . 1999;34(2):235-41.

Johnson CD, Puntis M. et al. Randomized, dose-finding phase III study of lithium gamolenate in patients with advanced pancreatic adenocarcinoma. Br J Surg . 2001 May;88(5):662-8.

Johnson CJ. Cancer incidence in an area of radioactive fallout downwind from the Nevada Test Site. JAMA . 1984 Jan 13;251(2):230-6.

Kakizoe T. Chemoprevention of cancer--focusing on clinical trials. Jpn J Clin Oncol . 2003 Sep;33(9):421-42.

Kaldor JM, Day NE. et al. Leukemia following Hodgkin's disease. N Engl J Med . 1990 Jan 4;322(1):7-13.

Kamada N, Tanaka K. et al. Chromosome aberrations and transforming genes in leukemic and non-leukemic patients with a history of atomic bomb exposure. Princess Takamatsu Symp . 1987;18:125-34.

Kang HK, Suh JH. et al. Induction of the differentiation of HL-60 promyelocytic leukemia cells by L-ascorbic acid. Free Radic Res . 2003 Jul;37(7):773-9.

Kennedy DD, Tucker KL. et al. Low antioxidant vitamin intakes are associated with increases in adverse effects of chemotherapy in children with acute lymphoblastic leukemia. Am J Clin Nutr . 2004 Jun;79(6):1029-36.

Kerr PE, DiGiovanna JJ. From vitamin to Vesanoid: systemic retinoids for the new millennium. Med Health R I . 2001 Jul;84(7):228-31.

Kisliuk RL. Deaza analogs of folic acid as antitumor agents. Curr Pharm Des . 2003;9(31):2615-25.

Komrokji RS, Lyman GH. The colony-stimulating factors: use to prevent and treat neutropenia and its complications. Expert Opin Biol Ther . 2004 Dec;4(12):1897-910.

Korte JE, Hertz-Picciotto I. et al. The contribution of benzene to smoking-induced leukemia. Environ Health Perspect . 2000 Apr;108(4):333-9.

Laurie SA, Miller VA. et al. Phase I study of green tea extract in patients with advanced lung cancer. Cancer Chemother Pharmacol . 2005 Jan;55(1):33-8.

Lee JJ, Kook H. et al. Immunotherapy using autologous monocyte-derived dendritic cells pulsed with leukemic cell lysates for acute myeloid leukemia relapse after autologous peripheral blood stem cell transplantation. J Clin Apheresis . 2004;19(2):66-70.

Lee R, Kim YJ. et al. The selective effect of genistein on the toxicity of bleomycin in normal lymphocytes and HL-60 cells. Toxicology . 2004 Feb 15;195(2-3):87-95.

Lee YK, Bone ND. et al. VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia. Blood . 2004 Aug 1;104(3):788-94.

Li HC, Yashiki S. et al. Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients. Jpn J Cancer Res . 2000 Jan;91(1):34-40.

Lian F, Li Y. et al. p53-independent apoptosis induced by genistein in lung cancer cells. Nutr Cancer . 1999;33(2):125-31.

Lin TS, Moran M. et al. Antibody therapy for chronic lymphocytic leukemia: a promising new modality. Hematol Oncol Clin North Am . 2004 Aug;18(4):895-x.

Linker CA. Autologous stem cell transplantation for acute myeloid leukemia. Bone Marrow Transplant . 2003 May;31(9):731-8.

Lissoni P, Bolis S. et al. A phase II study of neuroimmunotherapy with subcutaneous low-dose IL-2 plus the pineal hormone melatonin in untreatable advanced hematologic malignancies. Anticancer Res . 2000 May;20(3B):2103-5.

Liu QY, Tan BK. Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. Life Sci . 2000;67(10):1207-18.

Lung HL, Ip WK. et al. Comparative study of the growth-inhibitory and apoptosis-inducing activities of black tea theaflavins and green tea catechin on murine myeloid leukemia cells. Int J Mol Med . 2004 Mar;13(3):465-71.

Lykkesfeldt J, Hagen TM. et al. Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation. FASEB J . 1998 Sep;12(12):1183-9.

Lyman GH, Kuderer N. et al. Evidence-based use of colony-stimulating factors in elderly cancer patients. Cancer Control . 2003 Nov;10(6):487-99.

Maisnar V, Chroust K. Treatment of associated anemia in different hematological disorders with epoetin alpha. Neoplasma . 2004;51(5):379-84.

Manley PW, Cowan-Jacob SW. et al. Imatinib: a selective tyrosine kinase inhibitor. Eur J Cancer . 2002 Sep;38 Suppl 5:S19-S27.

Mann G, Reinhardt D. et al. Treatment with all-trans retinoic acid in acute promyelocytic leukemia reduces early deaths in children. Ann Hematol . 2001 Jul;80(7):417-22.

McDonald TA, Holland NT. et al. Hypothesis: phenol and hydroquinone derived mainly from diet and gastrointestinal flora activity are causal factors in leukemia. Leukemia . 2001 Jan;15(1):10-20.

McFarland JT, Kuzma C. et al. Palliative irradiation of the spleen. Am J Clin Oncol . 2003 Apr;26(2):178-83.

McNeil DE, Cote TR. et al. SEER update of incidence and trends in pediatric malignancies: acute lymphoblastic leukemia. Med Pediatr Oncol . 2002 Dec;39(6):554-7.

Meinert R, Schuz J. et al. Leukemia and non-Hodgkin's lymphoma in childhood and exposure to pesticides: results of a register-based case-control study in Germany. Am J Epidemiol . 2000 Apr 1;151(7):639-46.

Mellibovsky L, Diez A. et al. Long-standing remission after 25-OH D3 treatment in a case of chronic myelomonocytic leukaemia. Br J Haematol . 1993 Dec;85(4):811-2.

Melo MB, Ahmad NN. et al. Mutations in the p53 gene in acute myeloid leukemia patients correlate with poor prognosis. Hematology . 2002 Feb;7(1):13-9.

Mendoza-Nunez VM, Retana-Ugalde R. et al. DNA damage in lymphocytes of elderly patients in relation with total antioxidant levels. Mech Ageing Dev . 1999 Apr 1;108(1):9-23.

Meyskens FL, Jr., Kopecky KJ. et al. Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial. Leuk Res . 1995 Sep;19(9):605-12.

Miyauchi J, Inatomi Y. et al. The in vitro effects of all-trans-retinoic acid and hematopoietic growth factors on the clonal growth and self-renewal of blast stem cells in acute promyelocytic leukemia. Leuk Res . 1997 Apr;21(4):285-94.

Miyazawa K, Yaguchi M. et al. Apoptosis/differentiation-inducing effects of vitamin K2 on HL-60 cells: dichotomous nature of vitamin K2 in leukemia cells. Leukemia . 2001 Jul;15(7):1111-7.

Morecki S, Revel-Vilk S. et al. Immunological evaluation of patients with hematological malignancies receiving ambulatory cytokine-mediated immunotherapy with recombinant human interferon-alpha 2a and interleukin-2. Cancer Immunol Immunother . 1992;35(6):401-11.

Moschovi M, Trimis G. et al. Serum lipid alterations in acute lymphoblastic leukemia of childhood. J Pediatr Hematol Oncol . 2004 May;26(5):289-93.

Nakajima H, Kizaki M. et al. All-trans and 9-cis retinoic acid enhance 1,25-dihydroxyvitamin D3-induced monocytic differentiation of U937 cells. Leuk Res . 1996 Aug;20(8):665-76.

Nakajima M, Toga W. Tyrosine kinase inhibitor as a therapeutic drug for chronic myelogenous leukemia and gastrointestinal stromal tumor. Nippon Yakurigaku Zasshi . 2003 Dec;122(6):482-90.

Nakano Y, Naoe T. et al. Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia. Eur J Haematol . 2000 Jul;65(1):23-31.

Nir I, Weiss L. et al. The use of melatonin and co-treatment with autologous or allogeneic cells as a model for control of malignant beta-cell leukemia. Adv Exp Med Biol . 1999;460:407-9.

Noshchenko AG, Zamostyan PV. et al. Radiation-induced leukemia risk among those aged 0-20 at the time of the Chernobyl accident: a case-control study in the Ukraine. Int J Cancer . 2002 Jun 1;99(4):609-18.

Okuno M, Kojima S. et al. Retinoids in cancer chemoprevention. Curr Cancer Drug Targets . 2004 May;4(3):285-98.

Park S, Han SS. et al. L-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms. Int J Biochem Cell Biol . 2004 Nov;36(11):2180-95.

Patlak M. Targeting leukemia: from bench to bedside. FASEB J . 2002 Mar;16(3):273.

Pedersen-Bjergaard J, Daugaard G. et al. Increased risk of myelodysplasia and leukaemia after etoposide, cisplatin, and bleomycin for germ-cell tumours. Lancet . 1991 Aug 10;338(8763):359-63.

Pedrono F, Martin B. et al. Natural alkylglycerols restrain growth and metastasis of grafted tumors in mice. Nutr Cancer . 2004;48(1):64-9.

Peiffert D, Hoffstetter S. [Radiotherapy in leukemia excluding total body irradiation]. Cancer Radiother . 1999 Mar;3(2):174-80.

Pisters KM, Newman RA. et al. Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol . 2001 Mar 15;19(6):1830-8.

Podar K, Anderson KC. The pathophysiological role of VEGF in hematological malignancies: therapeutic implications. Blood . 2004 Oct 7.

Pugliese PT, Jordan K. et al. Some biological actions of alkylglycerols from shark liver oil. J Altern Complement Med . 1998;4(1):87-99.

Purasiri P, Mckechnie A. et al. Modulation in vitro of human natural cytotoxicity, lymphocyte proliferative response to mitogens and cytokine production by essential fatty acids. Immunology . 1997 Oct;92(2):166-72.

Quintas-Cardama A, Kantarjian H. et al. Granulocyte-colony-stimulating factor (filgrastim) may overcome imatinib-induced neutropenia in patients with chronic-phase chronic myelogenous leukemia. Cancer . 2004 Jun 15;100(12):2592-7.

Quirt I, Robeson C. et al. Epoetin alfa therapy increases hemoglobin levels and improves quality of life in patients with cancer-related anemia who are not receiving chemotherapy and patients with anemia who are receiving chemotherapy. J Clin Oncol . 2001 Nov 1;19(21):4126-34.

raghi-Niknam M, Liang B. et al. Modulation of immune dysfunction during murine leukaemia retrovirus infection of old mice by dehydroepiandrosterone sulphate (DHEAS). Immunology . 1997 Mar;90(3):344-9.

Rauscher GH, Shore D. et al. Hair dye use and risk of adult acute leukemia. Am J Epidemiol . 2004 Jul 1;160(1):19-25.

Reiffers J, Stoppa AM. et al. Allogeneic vs autologous stem cell transplantation vs chemotherapy in patients with acute myeloid leukemia in first remission: the BGMT 87 study. Leukemia . 1996 Dec;10(12):1874-82.

Rinsky RA, Young RJ. et al. Leukemia in benzene workers. Am J Ind Med . 1981;2(3):217-45.

Ritz J, Schlossman SF. Utilization of monoclonal antibodies in the treatment of leukemia and lymphoma. Blood . 1982 Jan;59(1):1-11.

Rock E, DeMichele A. Nutritional approaches to late toxicities of adjuvant chemotherapy in breast cancer survivors. J Nutr . 2003 Nov;133(11 Suppl 1):3785S-93S.

Russell RM. The aging process as a modifier of metabolism. Am J Clin Nutr . 2000 Auga;72(2 Suppl):529S-32S.

Sacchi S, Russo D. et al. All-trans retinoic acid in hematological malignancies, an update. GER (Gruppo Ematologico Retinoidi). Haematologica . 1997 Jan;82(1):106-21.

Sandler DP. Recent studies in leukemia epidemiology. Curr Opin Oncol . 1995 Jan;7(1):12-8.

Sandler DP, Shore DL. et al. Cigarette smoking and risk of acute leukemia: associations with morphology and cytogenetic abnormalities in bone marrow. J Natl Cancer Inst . 1993 Dec 15;85(24):1994-2003.

Saven A, Burian C. et al. Long-term follow-up of patients with hairy cell leukemia after cladribine treatment. Blood . 1998 Sep 15;92(6):1918-26.

Scagliotti GV, Shin DM. et al. Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma. J Clin Oncol . 2003 Apr 15;21(8):1556-61.

Schoch C, Kern W. et al. Dependence of age-specific incidence of acute myeloid leukemia on karyotype. Blood . 2001 Dec 1;98(12):3500.

Sen CK, Roy S. et al. Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. Free Radic Biol Med . 1997;22(7):1241-57.

Sen CK, Sashwati R. et al. Fas mediated apoptosis of human Jurkat T-cells: intracellular events and potentiation by redox-active alpha-lipoic acid. Cell Death Differ . 1999 May;6(5):481-91.

Singh JN, Chansouria JP. et al. Blood bioamines, cortisol and aminoacid levels in leukemic patients. Indian J Cancer . 1989 Dec;26(4):222-6.

Singh V, Kharb S. et al. Serum vitamin E in chronic myeloid leukaemia. J Assoc Physicians India . 2000 Feb;48(2):201-3.

Skibola CF, Smith MT. et al. Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood . 2002 May 15;99(10):3786-91.

Skrede B, Lie SO. et al. Uptake and storage of retinol and retinyl esters in bone marrow of children with acute myeloid leukemia treated with high-dose retinyl palmitate. Eur J Haematol . 1994 Mar;52(3):140-4.

Smith MA, McCaffrey RP. et al. The secondary leukemias: challenges and research directions. J Natl Cancer Inst . 1996 Apr 3;88(7):407-18.

Sokoloski JA, Hodnick WF. et al. Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3: possible relationship to NF-kappaB. Leukemia . 1997 Sep;11(9):1546-53.

Srivastava MD, Ambrus JL. Effect of 1,25(OH)2 Vitamin D3 analogs on differentiation induction and cytokine modulation in blasts from acute myeloid leukemia patients. Leuk Lymphoma . 2004 Oct;45(10):2119-26.

St CM, Kennett MJ. et al. Vitamin A toxicity and vitamin E deficiency in a rabbit colony. Contemp Top Lab Anim Sci . 2004 Jul;43(4):26-30.

Su JL, Lin MT. et al. Resveratrol induces FasL-related apoptosis through Cdc42 activation of ASK1/JNK-dependent signaling pathway in human leukemia HL-60 cells. Carcinogenesis . 2005 Jan;26(1):1-10.

Thompson JR, Gerald PF. et al. Maternal folate supplementation in pregnancy and protection against acute lymphoblastic leukaemia in childhood: a case-control study. Lancet . 2001 Dec 8;358(9297):1935-40.

Tilyou SM. BEIR V report. Experts urge cautious interpretation of higher risk estimates. J Nucl Med . 1990 Apr;31(4):13A-9A.

Uchiyama T. Human T cell leukemia virus type I (HTLV-I) and human diseases. Annu Rev Immunol . 1997;15:15-37.

Uozumi K, Uematsu T. et al. Serum dehydroepiandrosterone and DHEA-sulfate in patients with adult T-cell leukemia and human T-lymphotropic virus type I carriers. Am J Hematol . 1996 Nov;53(3):165-8.

Vera P, Rohrlich P. et al. Contribution of single-photon emission computed tomography in the diagnosis and follow-up of CNS toxicity of a cytarabine-containing regimen in pediatric leukemia. J Clin Oncol . 1999 Sep;17(9):2804-10.

Visani G, Baravelli S. et al. Slimming diet and the development of acute leukemia: a possible relationship? Report of three cases. Leuk Lymphoma . 1997 Jun;26(1-2):181-3.

Walle T, Hsieh F. et al. High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab Dispos . 2004 Dec;32(12):1377-82.

Wang H, Rajagopal S. et al. Differentiation-promoting effect of 1-O (2 methoxy) hexadecyl glycerol in human colon cancer cells. J Cell Physiol . 1999 Feb;178(2):173-8.

Wickramasinghe SN, Fida S. Bone marrow cells from vitamin B12- and folate-deficient patients misincorporate uracil into DNA. Blood . 1994 Mar 15;83(6):1656-61.

Xie Y, Davies SM. et al. Trends in leukemia incidence and survival in the United States (1973-1998). Cancer . 2003 May 1;97(9):2229-35.

Xu B, Monsarrat B. et al. Effect of ajoene, a natural antitumor small molecule, on human 20S proteasome activity in vitro and in human leukemic HL60 cells. Fundam Clin Pharmacol . 2004 Apr;18(2):171-80.

Xu YX, Pindolia KR. et al. Curcumin inhibits IL1 alpha and TNF-alpha induction of AP-1 and NF-kB DNA-binding activity in bone marrow stromal cells. Hematopathol Mol Hematol . 1997;11(1):49-62.

Yaguchi M, Miyazawa K. et al. Vitamin K2 and its derivatives induce apoptosis in leukemia cells and enhance the effect of all-trans retinoic acid. Leukemia . 1997 Jun;11(6):779-87.

Yamauchi T, Shirasaki H. et al. Pure red cell aplasia developing into myeloproliferation with myelodysplasia and subsequent leukemia after cyclosporin A therapy. Int J Hematol . 2002 Jun;75(5):514-8.

Zheng A, Savolainen ER. et al. All-trans retinoic acid combined with interferon-alpha effectively inhibits granulocyte-macrophage colony formation in chronic myeloid leukemia. Leuk Res . 1996 Mar;20(3):243-8.

Zinzani PL, Levrero MG. et al. Alpha-interferon as maintenance drug after initial fludarabine therapy for patients with chronic lymphocytic leukemia and low-grade non-Hodgkin's lymphoma. Haematologica . 1994 Jan;79(1):55-60.


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