Anxiety

References

Abdali K, Khajehei M, Tabatabaee HR. Effect of St John's wort on severity, frequency, and duration of hot flashes in premenopausal, perimenopausal and postmenopausal women: a randomized, double-blind, placebo-controlled study. Menopause. 2010 Mar;17(2):326-31.

Abdou AM, Higashiguchi S, Horie K et al: Relaxation and immunity enhancement effects of gamma aminobutyric acid (GABA) administration in humans. Biofactors, 2006; 26(3): 201–8

Al-Akoum M et al. Effects of Hypericum perforatum (St. John's wort) on hot flashes and quality of life in perimenopausal women: a randomized pilot trial. opause. 2009 Mar-Apr;16(2):307-14.

Amsterdam JD, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J. A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. J Clin Psychopharmacol. 2009 Aug;29(4):378-82.

Anacker C et al. Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor. Mol Psychiatry. 2011 Jul;16(7):738-50. doi: 10.1038/mp.2011.26. Epub 2011 Apr 12.

Andrade C. Ashwagandha for anxiety disorders.World J Biol Psychiatry. 2009;10(4 Pt 2):686-7.

Andreatini R, Sartori VA, Seabra ML, Leite JR: sEffect of valepotriates (valerian extract) in generalized anxiety disorder: a randomized placebo- controlled pilot study. Phytother Res, 2002; 16(7): 650–54

Appleton KM, Rogers PJ, Ness AR. Is there a role for n-3 long-chain polyunsaturated fatty acids in the regulation of mood and behaviour? A review of the evidence to date from epidemiological studies, clinical studies and intervention trials. Nutr Res Rev. 2008 Jun;21(1):13-41.

Ara I, Bano S. St. John's Wort modulates brain regional serotonin metabolism in swim stressed rats. Pak J Pharm Sci. 2009 Jan;22(1):94-101.

Awad R, Levac D, Cybulska P et al: Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system. Can J Physiol Pharmacol, 2007; 85(9): 933–42

Bargellini A, Piccinini L, De Palma M, Giacobazzi P, Scaltriti S, Mariano M, Roncaglia R, Borella P. Trace elements, anxiety and immune parameters in patients affected by cancer. J Trace Elem Med Biol. 2003;17 Suppl 1:3-9.

Bazil CW, Battista J, Basner RC: Gabapentinimproves sleep in the presence of alcohol. J Clin SleepMed, 2005; 1: 284–87

Beacher FD, Gray MA, Minati L, Whale R, Harrison NA, Critchley HD. Acute tryptophan depletion attenuates conscious appraisal of social emotional signals in healthy female volunteers. Psychopharmacology (Berl). 2011 Feb;213(2-3):603-13.

Belcaro G, Cesarone MR, Cornelli U, Dugall M. MF Afragil® in the treatment of 34 menopause symptoms: a pilot study. Panminerva Med. 2010 Jun;52(2 Suppl 1):49-54.

Benke D, Barberis A, Kopp S et al: GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts. Neuropharmacology. 2009; 56(1): 174–81

Benton D, Cook R. Selenium supplementation improves mood in a double-blind crossover trial. Psychopharmacology (Berl). 1990;102(4):549-50.

Benton D, Cook R. The impact of selenium supplementation on mood. Biol Psychiatry. 1991 Jun 1;29(11):1092-8.

Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine. 2000 Dec;7(6):463-9.

Bhattacharyya D, Jana U, Debnath PK, Sur TK: Initial exploratory observational pharmacology of Valeriana wallichii on stress management: a clinical report. Nepal Med Coll J, 2007; 9(1): 36–39

Bienvenu OJ, Wuyek LA, Stein MB. Anxiety disorders diagnosis: some history and controversies. Curr Top Behav Neurosci. 2010;2:3-19.

Binder EB et al. The CRF system, stress, depression and anxiety-insights from human genetic studies. Mol Psychiatry. 2010 Jun;15(6):574-88. Epub 2009 Dec 15.

Binder G, Weber S, Ehrismann M, Zaiser N, Meisner C, Ranke MB, Maier L, Wudy SA, Hartmann MF, Heinrich U, Bettendorf M, Doerr HG, Pfaeffle RW, Keller E; and the South German Working Group for Pediatric Endocrinology. Effects of dehydroepiandrosterone therapy on pubic hair growth and psychological well-being in adolescent girls and young women with central adrenal insufficiency: a double-blind, randomized, placebo-controlled phase III trial. J Clin Endocrinol Metab. 2009 Apr;94(4):1182-90.

Bloch M, Azem F, Aharonov I, Ben Avi I, Yagil Y, Schreiber S, Amit A, Weizman A. GnRH-agonist induced depressive and anxiety symptoms during in vitro fertilization-embryo transfer cycles. Fertil Steril. 2011

Bonnefont-Rousselot D, Collin F. Melatonin: action as antioxidant and potential applications in human disease and aging. Toxicology. 2010 Nov 28;278(1):55-67.

Bourin M, Lambert O. Pharmacotherapy of anxious disorders. Hum Psychopharmacol Clin Exp. 2002;17:383–400.

Bulloch AG, Currie S, Guyn L, Williams JV, Lavorato DH, Patten SB.Estimates of the treated prevalence of bipolar disorders by mental health services in the general population: comparison of results from administrative and health survey data. Chronic Dis Inj Can. 2011 Jun;31(3):129-34.

Buydens-Branchey L, Branchey M, Hibbeln JR. Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):568-75.

Cagnacci A, Arangino S, Renzi A, Zanni AL, Malmusi S, Volpe A. Kava-Kava administration reduces anxiety in perimenopausal women. Maturitas. 2003;44:103–109.

Camfield DA, Sarris J, Berk M. Nutraceuticals in the treatment of obsessive compulsive disorder (OCD): a review of mechanistic and clinical evidence. Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1;35(4):887-95. Epub 2011 Feb 23.

Canning S, Waterman M, Orsi N, Ayres J, Simpson N, Dye L. The efficacy of Hypericum perforatum (St John's wort) for the treatment of premenstrual syndrome: a randomized, double-blind, placebo-controlled trial. CNS Drugs. 2010 Mar 1;24(3):207-25.

Cantor C. Post-traumatic stress disorder: evolutionary perspectives. Aust N Z J Psychiatry. 2009 Nov;43(11):1038-48.

Carek PJ, Laibstain SE, Carek SM. Exercise for the treatment of depression and anxiety. Int J Psychiatry Med. 2011;41(1):15-28.

Carroll D, Ring C, Suter M, Willemsen G. The effects of an oral multivitamin combination with calcium, magnesium, and zinc on psychological well-being in healthy young male volunteers: a double-blind placebo-controlled trial. Psychopharmacology (Berl). 2000 Jun;150(2):220-5.

Chiappedi M, Bejor M. Herbals and natural dietary supplements in psychiatric practice. Recent Pat CNS Drug Discov. 2010 Jun;5(2):164-71.

Cho HS, Kim S, Lee SY, Park JA, Kim SJ, Chun HS. Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death. Neurotoxicology. 2008 Jul;29(4):656-62.

Cloos JM, Ferreira V. Current use of benzodiazepines in anxiety disorders. Curr Opin Psychiatry. 2009 Jan;22(1):90-5.

Coelho CM, Gonçalves DC, Purkis H, Pocinho M, Pachana NA, Byrne GJ. Specific phobias in older adults: characteristics and differential diagnosis. Int Psychogeriatr. 2010 Aug;22(5):702-11.

Cooley K, Szczurko O, Perri D, Mills EJ, Bernhardt B, Zhou Q, Seely D. Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974. PLoS One. 2009 Aug 31;4(8):e6628.

Coppen A et al. Treatment of depression: time to consider folic acid and vitamin B12. J Psychopharmacol. 2005 Jan;19(1):59-65.

Cubeddu A, Giannini A, Bucci F, Merlini S, Casarosa E, Pluchino N, Luisi S, Luisi M, Genazzani AR. Paroxetine increases brain-derived neurotrophic factor in postmenopausal women. Menopause. 2010 Mar;17(2):338-43.

Culpepper L. Generalized anxiety disorder and medical illness. J Clin Psychiatry. 2009;70 Suppl 2:20-4.

Cunningham J, Yonkers KA, O'Brien S, Eriksson E. Update on research and treatment of premenstrual dysphoric disorder. Harv Rev Psychiatry. 2009;17(2):120-37.

De Souza MC et al. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study. J Womens Health Gend Based Med. 2000 Mar;9(2):131-9.

De Souza MC, Walker AF, Robinson PA, Bolland K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study. J Womens Health Gend Based Med. 2000 Mar;9(2):131-9.

Deng G, Cassileth BR, Yeung KS. Complementary therapies for cancer-related symptoms. J Support Oncol. 2004 Sep-Oct;2(5):419-26; discussion 427-9.

Dimpfel W, Pischel I, Lehnfeld R: Effects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activityof volunteers. Eur J Med Res, 2004; 9(9): 423–31

Dimpfel W, Suter A: Sleep improving effects of a single dose administration of a valerian/hops fluid extract – a double blind, randomized, placebo-controlled sleep-EEG study in a parallel design using electrohypnograms. Eur J Med Res, 2008; 13(5): 200–4

Durant C, Christmas D, Nutt D. The pharmacology of anxiety. Curr Top Behav Neurosci. 2010;2:303-30.

Facial affect processing in social anxiety: tasks and stimuli. J Neurosci Methods. 2010 Oct 30;193(1):1-6.

Faustino TT, de Almeida RB, Andreatini R. Medicinal plants for the treatment of generalized anxiety disorder: a review of controlled clinical studies. Rev Bras Psiquiatr. 2010 Dec;32(4):429-36.

Fernstrom JD, Fernstrom MH. Tyrosine, phenylalanine, and catecholamine synthesis and function in the brain. J Nutr. 2007 Jun;137(6 Suppl 1):1539S-1547S; discussion 1548S.

Feurte S, Gerozissis K et al. Plasma Trp/LNAA ratio increases during chronic ingestion of an alpha-lactalbumin diet in rats. Nutr Neurosci. 2001;4(5):413–8.

Field T, Diego M, Hernandez-Reif M. Tai chi/yoga effects on anxiety, heartrate, EEG and math computations. Complement Ther Clin Pract. 2010 Nov;16(4):235-8.

Froy O. Cytochrome P450 and the biological clock in mammals. Curr Drug Metab. 2009 Feb;10(2):104-15.

Ghosh S, Smriga M, Vuvor F, Suri D, Mohammed H, Armah SM, Scrimshaw NS. Effect of lysine supplementation on health and morbidity in subjects belonging to poor peri-urban households in Accra, Ghana. Am J Clin Nutr. 2010 Oct;92(4):928-39

Goodwin RD, Davidson KW, Keyes K. Mental disorders and cardiovascular disease among adults in the United States. J Psychiatr Res. 2009 Jan;43(3):239-46.

Gosney MA, Hammond MF, Shenkin A, Allsup S. Effect of micronutrient supplementation on mood in nursing home residents. Gerontology. 2008;54(5):292-9.

Gureje O. Comorbidity of pain and anxiety disorders.Curr Psychiatry Rep. 2008 Aug;10(4):318-22.

Hadjikhani R: Anxiolytic-like Effects of Dichloromethane Extracts of Valerian (DEV) in Adult Male Wistar Rats. World Academy of Science, Engineering and Technology, 2009; (55): 532–36

Hanus M, Lafon J, Mathieu M. Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders. Curr Med Res Opin. 2004 Jan;20(1):63-71.

Hattesohl M, Feistel B, Sievers H et al: Extracts of Valeriana offi cinalis L.s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties. Phytomedicine, 2008; 15(1–2): 2–15

Head KA, Kelly GS. Nutrients and botanicals for treatment of stress: adrenal fatigue, neurotransmitter imbalance, anxiety, and restless sleep. Altern Med Rev. 2009 Jun;14(2):114-40.

Heese T, Jenkinson J, Love C, Milam R, Perkins L, Adams C, McCall S, Ceremuga TE. Anxiolytic effects of L-theanine--a component of green tea--when combined with midazolam, in the male Sprague-Dawley rat. AANA J. 2009 Dec;77(6):445-9.

Hood SD, Hince DA, Davies SJ, Argyropoulos S, Robinson H, Potokar J, Nutt DJ. Effects of acute tryptophan depletion in serotonin reuptake inhibitor-remitted patients with generalized anxiety disorder. Psychopharmacology (Berl). 2010 Feb;208(2):223-32.

Hunot V, Churchill R, Silva de Lima M, Teixeira V. Psychological therapies for generalised anxiety disorder. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD001848.

Iezhitsa IN, Spasov AA, Kharitonova MV, Kravchenko MS. Effect of magnesium chloride on psychomotor activity, emotional status, and acute behavioural responses to clonidine, d-amphetamine, arecoline, nicotine, apomorphine, and L-5-hydroxytryptophan. Nutr Neurosci. 2011 Jan;14(1):10-24.

Ishiwata N, Melby MK, Mizuno S, Watanabe S. New equol supplement for relieving menopausal symptoms: randomized, placebo-controlled trial of Japanese women. Menopause. 2009 Jan-Feb;16(1):141-8.

Javnbakht M, Hejazi Kenari R, Ghasemi M. Effects of yoga on depression and anxiety of women. Complement Ther Clin Pract. 2009 May;15(2):102-4.

Jezova D, Hlavacova N. Endocrine factors in stress and psychiatric disorders: focus on anxiety and salivary steroids. Ann N Y Acad Sci. 2008 Dec;1148:495-503.

Jezova D, Makatsori A, Smriga M, Morinaga Y, Duncko R. Subchronic treatment with amino acid mixture of L-lysine and L-arginine modifies neuroendocrine activation during psychosocial stress in subjects with high trait anxiety. Nutr Neurosci. 2005 Jun;8(3):155-60.

Jung KI, Ock SM, Chung JH, Song CH. Associations of serum Ca and Mg levels with mental health in adult women without psychiatric disorders. Biol Trace Elem Res. 2010 Feb;133(2):153-61.

Kakuda T. Neuroprotective effects of theanine and its preventive effects on cognitive dysfunction. Pharmacol Res. 2011 Aug;64(2):162-8.

Kalman DS, Feldman S, Feldman R et al: Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women: a pilot, double-blind, placebo-controlled clinical trial. Nutr J, 2008; 7: 11

Karten YJ et al. Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons. Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13456-61.

Kendell SF, Krystal JH, Sanacora G: GABA andglutamate systems as therapeutic targets in depressionand mood disorders. Expert Opin Ther Targets, 2005; 9: 153–68

Kennedy DO, Little W, Haskell CF, Scholey AB: Anxiolytic effects of a combination of Melissa officinalis and Valeriana offi cinalis during laboratory induced stress. Phytother Res, 2006; 20(2): 96–102

Kennedy DO, Little W, Scholey AB: Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med, 2004; 66(4): 607–13

Kessler RC, Berglund PA, Demler O, Jin R, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Archives of General Psychiatry. 2005 Jun;62(6):593-602.

Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey Replication (NCS-R). Archives of General Psychiatry, 2005 Jun;62(6):617-27.

Kessler RC, Ruscio AM, Shear K, Wittchen HU. Epidemiology of anxiety disorders. Curr Top Behav Neurosci. 2010;2:21-35.

Khom S, Baburin I, Timin E et al: Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specifi city. Neuropharmacology, 2007; 53(1): 178–87

Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Glaser R. Omega-3 supplementation lowers inflammation and anxiety in medical students: A randomized controlled trial. Brain Behav Immun. 2011

Kikuchi H, Nakatani Y, Seki Y, Yu X, Sekiyama T, Sato-Suzuki I, Arita H. Decreased blood serotonin in the premenstrual phase enhances negative mood in healthy women.J Psychosom Obstet Gynaecol. 2010 Jun;31(2):83-9.

Koetter U, Schrader E, Kaufeler R, Brattstrom A: A randomized, double blind, placebo-controlled, prospective clinical study to demonstrate clinical efficacy of a fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder. Phytother Res, 2007; 21(9): 847–51

Krugers HJ et al. Chronic stress effects on hippocampal structure and synaptic function: relevance for depression and normalization by anti-glucocorticoid treatment. Front Synaptic Neurosci. 2010 Jul 12;2:24.

Kugaya A, Sanacora G: Beyond monoamines: glutamatergic function in mood disorders. CNS Spectr, 2005; 10: 808–19

Kulkarni SK, Singh K, Bishnoi M.Comparative behavioural profile of newer antianxiety drugs on different mazes. Indian J Exp Biol. 2008 Sep;46(9):633-8.

Kuribara H, Weintraub ST, Yoshihama T, Maruyama Y. An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice. J Nat Prod. 2003 Oct;66(10):1333-7.

Lakhan SE, Vieira KF. Nutritional therapies for mental disorders. Nutr J. 2008 Jan 21;7:2.

Larroy García C, Gómez-Calcerrada SG. Cognitive-behavioral intervention among women with slight menopausal symptoms: a pilot study. Span J Psychol. 2011 May;14(1):344-55.

Lee J, Kim KW, Kim HK, Chae SW, Jung JC, Kwon SH, Rheu CH. The effect of Rexflavone (Sophorae fructus extract) on menopausal symptoms in postmenopausal women: a randomized double-blind placebo controlled clinical trial. Arch Pharm Res. 2010 Apr;33(4):523-30. Epub 2010 Apr 27.

Levine J et al. Elevated serum homocysteine levels in male patients with PTSD. Depress Anxiety. 2008;25(11):E154-7.

Lewis BA, Martinson BC, Sherwood NE, Avery MD. A pilot study evaluating a telephone-based exercise intervention for pregnant and postpartum women. J Midwifery Womens Health. 2011 Mar-Apr;56(2):127-31.

Linde K, Berner MM, Kriston L. St John's wort for major depression. Cochrane Database Syst Rev. 2008 Oct 8;(4):CD000448.

Linde K. St. John's wort - an overview.Forsch Komplementmed. 2009 Jun;16(3):146-55.

Lipovac M, Chedraui P, Gruenhut C, Gocan A, Stammler M, Imhof M. Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts.Maturitas. 2010 Mar;65(3):258-61.

Lu K, Gray MA et al. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Hum Psychopharmacol. 2004 Oct;19(7):457–65.

Machado-de-Sousa JP, Arrais KC, Alves NT, Chagas MH, de Meneses-Gaya C, Crippa JA, Hallak JE.

Malsch U, Kieser M. Efficacy of kava-kava in the treatment of non-psychotic anxiety, following pretreatment with benzodiazepines. Psychopharmacology (Berl) 2001;157:277–283.

Mannel M, Kuhn U, Schmidt U, Ploch M, Murck H. St. John's wort extract LI160 for the treatment of depression with atypical features - a double-blind, randomized, and placebo-controlled trial. J Psychiatr Res. 2010 Sep;44(12):760-7.

Mannel M.Drug interactions with St John's wort : mechanisms and clinical implications. Drug Saf. 2004;27(11):773-97.

Maron E, Toru I et al. The effect of 5-hydroxytryptophan on cholecystokinin-4-induced panic attacks in healthy volunteers. J Psychopharmacol. 2004 Jun;18(2):194–9.

McRee LD, Noble S, Pasvogel A. Using massage and music therapy to improve postoperative outcomes. AORN J. 2003 Sep;78(3):433-42, 445-7.

Merlo LJ, Storch EA. Obsessive-compulsive disorder: tools for recognizing its many expressions. J Fam Pract. 2006 Mar;55(3):217-22.

Michel JL, Chen Y, Zhang H, Huang Y, Krunic A, Orjala J, Veliz M, Soni KK, Soejarto DD, Caceres A, Perez A, Mahady GB. Estrogenic and serotonergic butenolides from the leaves of Piper hispidum Swingle (Piperaceae). J Ethnopharmacol. 2010 May 27;129(2):220-6.

Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev. 2000 Aug;5(4):334-46.

Mohan L, Rao US, Gopalakrishna HN, Nair V. Evaluation of the Anxiolytic Activity of NR-ANX-C (a Polyherbal Formulation) in Ethanol Withdrawal-Induced Anxiety Behavior in Rats. Evid Based Complement Alternat Med. 2011;2011.

Mokhber N, Namjoo M, Tara F, Boskabadi H, Rayman MP, Ghayour-Mobarhan M, Sahebkar A, Majdi MR, Tavallaie S, Azimi-Nezhad M, Shakeri MT, Nematy M, Oladi M, Mohammadi M, Ferns G. Effect of supplementation with selenium on postpartum depression: a randomized double-blind placebo-controlled trial. J Matern Fetal Neonatal Med. 2011 Jan;24(1):104-8.

Movafegh A, Alizadeh R, Hajimohamadi F et al: Preoperative oral Passiflora incarnata reduces anxiety in ambulatory surgery patients: a double-blind, placebo-controlled study. Anesth Analg, 2008; 106(6): 1728–32

Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, Volpini G, Benvenuti C. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006 Aug;58(4):323-34.

Muller SF, Klement S: A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine, 2006; 13(6): 383–87

Nathan PJ, Burrows GD et al. Subsensitive melatonin suppression by dim white light: Possible biological marker of panic disorder. Int J Neuropsychopharmacol. 1998 Dec;1(2):115–120.

Nemeroff CB: The role of GABA in thepathophysiology and treatment of anxiety disorders. Psychopharmacol Bull, 2003; 37: 133–46

Ortiz JG, Nieves-Natal J, Chavez P: Effects of Valeriana offi cinalis extractson [3H]fl unitrazepam binding, synaptosomal [3H]GABA uptake, and hippocampal [3H]GABA release. Neurochem Res, 1999; 24(11): 1373–78

Panossian A, Wikman G, Sarris J. Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine. 2010 Jun;17(7):481-93.

Parcells DA. Women's mental health nursing: depression, anxiety and stress during pregnancy.J Psychiatr Ment Health Nurs. 2010 Nov;17(9):813-20.

Pellino TA, Gordon DB, Engelke ZK, Busse KL, Collins MA, Silver CE, Norcross NJ. Use of nonpharmacologic interventions for pain and anxiety after total hip and total knee arthroplasty. Orthop Nurs. 2005 May-Jun;24(3):182-90

Perica MM, Delas I. Essential Fatty acids and psychiatric disorders. Nutr Clin Pract. 2011 Aug;26(4):409-25.

Ramanathan M, Balaji B, Justin A. Behavioural and neurochemical evaluation of Perment an herbal formulation in chronic unpredictable mild stress induced depressive model. Indian J Exp Biol. 2011 Apr;49(4):269-75.

Ringbäck Weitoft G, Rosén M. Is perceived nervousness and anxiety a predictor of premature mortality and severe morbidity? A longitudinal follow up of the Swedish survey of living conditions. J Epidemiol Community Health. 2005 Sep;59(9):794-8.

Risbrough V. Behavioral correlates of anxiety. Curr Top Behav Neurosci. 2010;2:205-28.

Roberson-Nay R, Kendler KS. Panic disorder and its subtypes: a comprehensive analysis of panic symptom heterogeneity using epidemiological and treatment seeking samples.Psychol Med. 2011 Apr 18:1-11

Rogers PJ, Hohoff C, Heatherley SV, Mullings EL, Maxfield PJ, Evershed RP, Deckert J, Nutt DJ.Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption. Neuropsychopharmacology. 2010 Aug;35(9):1973-83.

Rogers PJ, Smith JE, Heatherley SV, Pleydell-Pearce CW. Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together. Psychopharmacology (Berl). 2008 Jan;195(4):569-77.

Roiser JP, Levy J, Fromm SJ, Wang H, Hasler G, Sahakian BJ, Drevets WC. The effect of acute tryptophan depletion on the neural correlates of emotional processing in healthy volunteers. Neuropsychopharmacology. 2008 Jul;33(8):1992-2006.

Ross BM Omega-3 polyunsaturated fatty acids and anxiety disorders. Prostaglandins Leukot Essent Fatty Acids. 2009 Nov-Dec;81(5-6):309-12.

Roy-Byrne PP, Wagner AW, Schraufnagel TJ. Understanding and treating panic disorder in the primary care setting. J Clin Psychiatry. 2005;66 Suppl 4:16-22.

Ruiz AD et al. Effectiveness of compounded bioidentical hormone replacement therapy: an observational cohort study. BMC Womens Health. 2011 Jun 8;11:27.

Saeed SA, Bloch RM, Antonacci DJ. Herbal and dietary supplements for treatment of anxiety disorders. Am Fam Physician. 2007 Aug 15;76(4):549-56.

Sarris J, Kavanagh DJ, Byrne G, Bone KM, Adams J, Deed G. The Kava Anxiety Depression Spectrum Study (KADSS): a randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum. Psychopharmacology (Berl) 2009;205:399–407.

Sarris J, Kavanagh DJ, Deed G, Bone KM. St. John's wort and Kava in treating major depressive disorder with comorbid anxiety: a randomised double-blind placebo-controlled pilot trial. Hum Psychopharmacol. 2009 Jan;24(1):41-8.

Sarris J, Kavanagh DJ. Kava and St. John's Wort: current evidence for use in mood and anxiety disorders. J Altern Complement Med. 2009 Aug;15(8):827-36.

Sarris J, Panossian A, Schweitzer I, Stough C, Scholey A. Herbal medicine for depression, anxiety and insomnia: A review of psychopharmacology and clinical evidence. Eur Neuropsychopharmacol. 2011 May 20.

Scherer J. Kava-kava extract in anxiety disorders: an outpatient observational study. Advances in Therapy. 1998;15:261–269.

Shippy RA et al. S-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS. BMC Psychiatry. 2004 Nov 11;4:38.

Shor-Posner G, Lecusay R, Miguez MJ, Moreno-Black G, Zhang G, Rodriguez N, Burbano X, Baum M, Wilkie F. Psychological burden in the era of HAART: impact of selenium therapy. Int J Psychiatry Med. 2003;33(1):55-69.

Slutsky I et al. Enhancement of learning and memory by elevating brain magnesium. Neuron. 2010 Jan 28;65(2):165-77.

Smriga M, Ando T, Akutsu M, Furukawa Y, Miwa K, Morinaga Y. Oral treatment with L-lysine and L-arginine reduces anxiety and basal cortisol levels in healthy humans. Biomed Res. 2007 Apr;28(2):85-90.

Smriga M, Ghosh S, Mouneimne Y, Pellett PL, Scrimshaw NS. Lysine fortification reduces anxiety and lessens stress in family members in economically weak communities in Northwest Syria. Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8285-8.

Smriga M, Torii K. L-Lysine acts like a partial serotonin receptor 4 antagonist and inhibits serotonin-mediated intestinal pathologies and anxiety in rats. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15370-5. Epub 2003 Dec 15.

Srinongkote S, Smriga M, Nakagawa K, Toride Y. A diet fortified with L-lysine and L-arginine reduces plasma cortisol and blocks anxiogenic response to transportation in pigs. Nutr Neurosci. 2003 Oct;6(5):283-9.

Streeter CC, Whitfield TH, Owen L, Rein T, Karri SK, Yakhkind A, Perlmutter R, Prescot A, Renshaw PF, Ciraulo DA, Jensen JE. Effects of yoga versus walking on mood, anxiety, and brain GABA levels: a randomized controlled MRS study. J Altern Complement Med. 2010 Nov;16(11):1145-52.

Strohle A et al. Stress responsive neurohormones in depression and anxiety. Pharmacopsychiatry. 2003 Nov;36 Suppl 3:S207-14.

Sundermann EE, Maki PM, Bishop JR.A review of estrogen receptor alpha gene (ESR1) polymorphisms, mood, and cognition. Menopause. 2010 Jul;17(4):874-86.

Tadros MG, Mohamed MR, Youssef AM, Sabry GM, Sabry NA, Khalifa AE. Involvement of serotoninergic 5-HT1A/2A, alpha-adrenergic and dopaminergic D1 receptors in St. John's wort-induced prepulse inhibition deficit: a possible role of hyperforin. Behav Brain Res. 2009 May 16;199(2):334-9.

Terzic MM et al. Influence of red clover-derived isoflavones on serum lipid profile in postmenopausal women. J Obstet Gynaecol Res. 2009 Dec;35(6):1091-5.

Thorne Research, Inc: Gamma-Aminobutyric Acid (GABA). Alternative Medicine Review, 2007; 12(3)

Toker L, Amar S, Bersudsky Y, Benjamin J, Klein E. The biology of tryptophan depletion and mood disorders. Isr J Psychiatry Relat Sci. 2010;47(1):46-55.

Tolin DF. Is cognitive-behavioral therapy more effective than other therapies? A meta-analytic review. Clin Psychol Rev. 2010 Aug;30(6):710-20.

Trauner G, Khom S, Baburin I et al: Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Med, 2008; 74(1): 19–24

van der Watt G, Laugharne J, Janca A. Complementary and alternative medicine in the treatment of anxiety and depression. Curr Opin Psychiatry. 2008 Jan;21(1):37-42.

van Die MD, Bone KM, Burger HG, Reece JE, Teede HJ. Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: findings from a subpopulation analysis. J Altern Complement Med. 2009 Sep;15(9):1045-8.

van Riel E et al. Chronic unpredictable stress causes attenuation of serotonin responses in cornu ammonis 1 pyramidal neurons. Neuroscience. 2003;120(3):649-58.

Walesiuk A, Braszko JJ. Preventive action of Ginkgo biloba in stress- and corticosterone-induced impairment of spatial memory in rats. Phytomedicine. 2009 Jan;16(1):40-6.

Watkins LL, K MC, J RD. Effect of kava extract on vagal cardiac control in generalized anxiety disorder: preliminary findings. Journal of psychopharmacology (Oxford, England) 2001;15:283–286.

Weeks BS. Formulations of dietary supplements and herbal extracts for relaxation and anxiolytic action: Relarian. Med Sci Monit. 2009 Nov;15(11):RA256-62.Weisberg RB. Overview of generalized anxiety disorder: epidemiology, presentation, and course. J Clin Psychiatry. 2009;70 Suppl 2:4-9.

Woelk H, Arnoldt KH, Kieser M, Hoerr R.Ginkgo biloba special extract EGb 761 in generalized anxiety disorder and adjustment disorder with anxious mood: a randomized, double-blind, placebo-controlled trial. J Psychiatr Res. 2007 Sep;41(6):472-80.

Wolfson P, Hoffmann DL: An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers. Altern Ther Health Med, 2003; 9(2):74–78

Wyrwich KW, Harnam N, Revicki DA, Locklear JC, Svedsater H, Endicott J. Assessment of quality of life enjoyment and satisfaction questionnaire-short form responder thresholds in generalized anxiety disorder and bipolar disorder studies. Int Clin Psychopharmacol. 2011 May;26(3):121-9.

Xu Q, Anderson D, Courtney M. A longitudinal study of the relationship between lifestyle and mental health among midlife and older women in Australia: findings from the Healthy Aging of Women Study. Health Care Women Int. 2010 Dec;31(12):1082-96.

Yehuda S, Rabinovitz S, Mostofsky DI. Mixture of essential fatty acids lowers test anxiety. Nutr Neurosci. 2005 Aug;8(4):265-7.