Testosterone, a natural anabolic steroid, can help place patients in a positive nitrogen balance. Dosages of 100-200 mg weekly can be given to most men and women. Consideration can be given to DHEA (see the DHEA Restoration Therapy protocol) and pregnenolone as well. The intravenous administration of vitamins (25-50 grams of vitamin C, 2-3 times weekly, in particular) may be helpful.
Testosterone supplementation in male HIV patients with wasting syndrome has been shown to increase lean body mass at weekly doses of 200mg administered intramuscularly. The most significant results were seen in combination with resistance weight training. In a study, 54 men were given testosterone or placebo and placed on a 12-week exercise training program or no training at all. Lean body mass and muscle increased in those undergoing training and testosterone therapy. Levels of beneficial HDL cholesterol increased in those training, but fell in those supplementing with testosterone. Viral load fell in those taking the hormone (Fairfield 2001).
Consideration should be given to "adrenal support." Patients with catabolic wasting should be assumed to have some degree of adrenal fatigue from the stress of chronic disease (see the Adrenal Disease protocol).
Warning: The possibilities discussed above have not been thoroughly studied with respect to potentially worsening cancer (if cancer is the source of the cachectic state). It is suggested that you discuss any potential treatment with a physician practicing complementary medicine prior to initiating therapy.