Life Extension Suggestions
Follow your physician's recommendations concerning the addition of daily dietary supplements. Multivitamins, minerals, and other supplements may be prescribed or recommended to help replace essential nutrients lost during dialysis treatments. Consult medical professionals experienced in treating kidney disorders and follow their treatment recommendations carefully. Establish appropriate dietary habits. The following supplements are supportive of overall kidney health. The recommendations are for healthy individuals. If you have any form of kidney disease, consult your physician before adding or changing any supplements you may currently be taking.
- Complete multi-vitamin: Per label instructions
- B-Complex vitamin: Per label instructions
- Pyridoxal 5’-phosphate (P5P): 100 mg daily
- Vitamin C: 1000 – 2000 mg daily
- Vitamin D: 5000 – 8000 IU daily (depending on blood test results; optimal levels are between 50 and 80 ng/ml)
- Vitamin E: 400 IU alpha-tocopherol and 200 mg gamma-tocopherol daily
- Calcium: 200 - 1200 mg daily
- Iron: 300 mg of iron protein succinylate, equivalent to 15 mg of elemental iron per capsule daily
- L-carnitine: 500 – 2000 mg daily
- CoQ10 (as ubiquinol): 100 – 200 mg daily
- Silymarin: 100 – 600 mg daily
- Curcumin (as highly absorbed BCM-95®): 400 – 800 mg daily
- Ginkgo biloba: standardized extract: 120 mg daily
- Resveratrol: 100 – 250 mg daily
- R-Lipoic acid: 240 – 480 mg daily
- Green tea (standardized extract): 725 mg daily
- Soy extract (containing up to 60 mg of isoflavones): twice daily
- Taurine: 2 – 3 grams (g) daily
- TMG (trimethylglycine): 500 – 2500 mg daily
- Omega-3 fish oil: 1400 mg EPA and 1000 mg DHA daily
- Dehydroepiandrosterone (DHEA): 25-50 mg daily (based on blood test results)
- Nettle: 120 – 240 mg daily
- N-acetyl cysteine (NAC): 600 – 1800 mg daily
- Vitamin K: 2100 mcg of vitamin K as 1000 mcg K1 and 1100 mcg K2 (as MK-4 and MK-7)
- Magnesium: 200 mg – 1000 mg daily
In addition, the following blood tests may provide helpful information.
- Chemistry Panel & Complete Blood Count (CBC)
- Cytokine Panel
- C-Reactive Protein
Overlooked Prescription Drug Kidneys are especially vulnerable to attack by proinflammatory cytokines. Pentoxifylline (PTX) is a drug that has been shown to protect against this type of kidney damage. The suggested dose of PTX is 400 mg twice daily.
PTX should not be used in patients with bleeding disorders such as those with recent cerebral or retinal hemorrhage. Patients taking Coumadin should have more frequently monitored prothrombin time. Those suffering from other types of bleeding should receive frequent physician examinations. Furthermore, consider having a physician evaluate coagulation status to see what effect PTX has on template bleeding time. This is an inexpensive test that relates to the biological effect of PTX or other agents like aspirin (non-steroidal anti-inflammatory agents) on platelet function. All of these agents affect platelet aggregation and this effect can be manifested in a prolonged template bleeding time. According to two studies, PTX should be avoided by Parkinson's patients. It is important to note that the body does use TNF-α to acutely fight infection(s). If patients are showing any sign of infectious disease, drugs like Enbrel® that inhibit the effects of TNF-α are temporarily discontinued. A new FDA advisory states that patients should be tested and treated for inactive, or latent tuberculosis prior to therapy with another TNF-α inhibiting therapy (eg, infliximab). Since PTX, fish oil, and nettle directly suppress TNF-α, perhaps these agents should be temporarily discontinued during the time when one has an active infection.
Disclaimer and Safety Information
This information (and any accompanying material) is not intended to replace the attention or advice of a physician or other qualified health care professional. Anyone who wishes to embark on any dietary, drug, exercise, or other lifestyle change intended to prevent or treat a specific disease or condition should first consult with and seek clearance from a physician or other qualified health care professional. Pregnant women in particular should seek the advice of a physician before using any protocol listed on this website. The protocols described on this website are for adults only, unless otherwise specified. Product labels may contain important safety information and the most recent product information provided by the product manufacturers should be carefully reviewed prior to use to verify the dose, administration, and contraindications. National, state, and local laws may vary regarding the use and application of many of the treatments discussed. The reader assumes the risk of any injuries. The authors and publishers, their affiliates and assigns are not liable for any injury and/or damage to persons arising from this protocol and expressly disclaim responsibility for any adverse effects resulting from the use of the information container herein.
The protocols raise many issues that are subject to change as new data emerge. None of our suggested protocol regimens can guarantee health benefits. The publisher has not performed independent verification of the data contained herein, and expressly disclaim responsibility for any error in literature.