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Health Concerns

Insomnia

References

American Academy of Family Physicians. Information from your family doctor: Insomnia: How to get a good night’s sleep. Am Fam Physician. 2005 Oct 1;72(7):1309–10.

Anderson GD, Elmer GW, et al. Pharmacokinetics of valerenic acid after administration of valerian in healthy subjects. Phytother Res. 2005 Sep;19(9):801–3.

Atkinson G, Holder A, et al. Effects of melatonin on the thermoregulatory responses to intermittent exercise. J Pineal Res. 2005 Nov;39(4):353–9.

Birdsall TC. 5-Hydroxytryptophan: A clinically-effective serotonin precursor. Altern Med Rev. 1998 Aug;3(4):271–80.

Burgess HJ, Crowley SJ, et al. Preflight adjustment to eastward travel: 3 days of advancing sleep with and without morning bright light. J Biol Rhythms. 2003 Aug;18(4):318–28.

Burgos I, Richter L, et al. Increased nocturnal interleukin-6 excretion in patients with primary insomnia: A pilot study. Brain Behav Immun. 2005 Aug 3.

Canani SF, John AB, et al. Prevalence of sleepiness in a group of Brazilian lorry drivers. Public Health. 2005 Oct;119(10):925–9.

Cavadas C, Araujo I, et al. In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on GABAA receptor in rat brain. Arzneimittelforschung. 1995;45:753–5.

Chen SW, Min L, et al. The effects of angelica essential oil in three murine tests of anxiety. Pharmacol Biochem Behav. 2004 Oct;79(2):377–82.

Copinschi G. Metabolic and endocrine effects of sleep deprivation. Essent Psychopharmacol. 2005;6(6):341–7.

Donovan JL, DeVane CL, et al. Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers. Drug Metab Dispos. 2004 Dec;32(12):1333–6.

Eastman CI, Gazda CJ, et al. Advancing circadian rhythms before eastward flight: A strategy to prevent or reduce jet lag. Sleep. 2005 Jan 1;28(1):33–44.

Erren TC, Reiter RJ, et al. The chronosense: What light tells man about biological time. Med Hypotheses. 2004;63(6):1074–80.

Graci G. Pathogenesis and management of cancer-related insomnia. J Support Oncol. 2005 Sep-Oct;3(5):349–59.

Guilleminault C, Do Kim Y, et al. Sleep and daytime sleepiness in upper airway resistance syndrome compared to obstructive sleep apnoea syndrome. Eur Respir J. 2001 May;17(5):838–47.

Gutierrez S, Ang-Lee MK, et al. Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteers. Pharmacol Biochem Behav. 2004 May;78(1):57–64.

Hadley S, Petry JJ. Valerian. Am Fam Physician. 2003 Apr 15;67(8):1755–8.

Herrera-Arellano A, Luna-Villegas G, et al. Polysomnographic evaluation of the hypnotic effect of Valeriana edulis standardized extract in patients suffering from insomnia. Planta Med. 2001 Nov;67(8):695–9.

Hudson C, Hudson SP, et al. Protein source tryptophan versus pharmaceutical grade tryptophan as an efficacious treatment for chronic insomnia. Nutr Neurosci. 2005 Apr;8(2):121–7.

Jefferson CD, Drake CL, et al. Sleep hygiene practices in a population-based sample of insomniacs. Sleep. 2005 May 1;28(5):611–5.

Kales A, Kales JD. Sleep disorders: Recent findings in the diagnosis and treatment of disturbed sleep. N Engl J Med. 1974;290:487–99.

Kennedy DO, Little W, et al. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004 Jul-Aug;66(4):607–13.

King AC, Oman RF, et al. Moderate-intensity exercise and self-rated quality of sleep in older adults. JAMA. 1997;277:32–7.

Kirkwood CK. Management of insomnia. J Am Pharm Assoc (Wash). 1999 Sep-Oct;39(5):688–96.

Krystal AD, Ressler I. The use of valerian in neuropsychiatry. CNS Spectr. 2001 Oct;6(10):841–7.

Kuhlmann J, Berger W, et al. The influence of valerian treatment on “reaction time, alertness and concentration” in volunteers. Pharmacopsychiatry. 1999;32:235–41.

Kupfersztain C, Rotem C, et al. The immediate effect of natural plant extract, Angelica sinensis and Matricaria chamomilla (Climex) for the treatment of hot flushes during menopause: A preliminary report. Clin Exp Obstet Gynecol. 2003;30(4):203–6.

Landolt HP, Borbely AA. [Alcohol and sleep disorders]. Ther Umsch. 2000 Apr;57(4):241–5.

Landolt HP, Roth C, et al. Late-afternoon ethanol intake affects nocturnal sleep and the sleep EEG in middle-aged men. J Clin Psychopharmacol. 1996 Dec;16(6):428–36.

Leathwood PD, Chauffard F. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav. 1982 Jul;17(1):65–71.

Leathwood PD, Chauffard F. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med. 1985;2:144–8.

Lefebvre T, Foster BC, et al. In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4. J Pharm Pharm Sci. 2004 Aug 12;7(2):265–73.

Leger D, Poursain B. An international survey of insomnia: Under-recognition and under-treatment of a ploysymptomatic condition. Curr Med Res Opin. 2005 Nov;21(11):1785–92.

Leigh JP. Employee and job attributes as predictors of absenteeism in a national sample of workers. Soc Sci Med. 1991;33:127–37.

Mahady GB. Black cohosh (Actaea/Cimicifuga racemosa): Review of the clinical data for safety and efficacy in menopausal symptoms. Treat Endocrinol. 2005;4(3):177–84.

Mazzoccoli G, Giuliani A. The hypothalamic-pituitary-thyroid axis and melatonin in humans: Possible interactions in the control of body temperature. Neuro Endocrinol Lett. 2004 Oct;25(5):368–72.

Melatonin [monograph]. Altern Med Rev. 2005 Dec;10(4):326–36.

Muller SF, Klement S. A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children. Phytomedicine. 2006 15 Feb.

Munch M, Knoblauch V, et al. Age-related attenuation of the evening circadian arousal signal in humans. Neurobiol Aging. 2005 Oct;26(9):1307–19.

Pandi-Perumal SR, Zisapel N, et al. Melatonin and sleep in aging population. Exp Gerontol. 2005 Dec;40(12):911–25.

Power JD, Perruccio AV, et al. Pain as a mediator of sleep problems in arthritis and other chronic conditions. Arthritis Rheum. 2005 Dec 15;53(6):911–9.

Rajput V, Bromley SM. Chronic insomnia: a practical review. Am Fam Physician. 1999 Oct 1;60(5):1431–8; discussion 1441–2.

Riemann D, Feige B, et al. [Diagnostics and therapy of sleep disorders in the general practice]. MMW Fortschr Med. 2005 May 17;147 Spec No 2:7–11.

Ringdahl EN, Pereira SL, et al. Treatment of primary insomnia. J Am Board Fam Pract. 2004 May-Jun;17(3):212–9.

Srinivasan V, Maestroni G, et al. Melatonin, immune function and aging. Immun Ageing. 2005 Nov 29;2:17.

Trevena L. Sleepless in Sydney: Is valerian an effective alternative to benzodiazepines in the treatment of insomnia? ACP J Club. 2004;141:A14–A16.

Valeriana officinalis [monograph]. Altern Med Rev. 2004 Dec;9(4):438–41.

Vgontzas AN, Bixler EO, et al. IL-6 and its circadian secretion in humans. Neuroimmunomodulation. 2005;12(3):131–40. Review.

Vgontzas AN, Zoumakis M, et al. Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime. Metabolism. 2002 Jul;51(7):887–92.

Wang JZ, Wang ZF. Role of melatonin in Alzheimer-like neurodegeneration. Acta Pharmacol Sin. 2006 Jan;27(1):41–9.

Yuan CS, Mehendale S, et al. The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesth Analg. 2004 Feb;98(2):353–8.

Zemlan FP, Mulchahey JJ, et al. The efficacy and safety of the melatonin agonist beta-methyl-6-chloromelatonin in primary insomnia: A randomized, placebo-controlled, crossover clinical trial. J Clin Psychiatry. 2005 Mar;66(3):384–90.

Ziegler G, Ploch M. Efficacy and tolerability of valerian extract LI 156 compared with oxazepam in the treatment of non-organic insomnia: A randomized, double-blind, comparative clinical study. Eur J Med Res. 2002 Nov 25;7(11):480–6.

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