Risk Factors for Alzheimer's Disease
Several factors influence the risk of Alzheimer’s disease. Some are modifiable, such as obesity and nutrient deficiencies, but others, such as carrying the ApoE4 gene, are not. Below is a partial list of factors known to be associated with an increased risk of Alzheimer’s disease (Yilmaz 2012; Daviglus 2011; Harrison 2012; Hinterberger 2012; Luchsinger 2012; van Himbergen 2012; Stern 2008; Blum 2012; Miklossy 2011).
- Advancing age
- Family history of Alzheimer’s disease
- Carrying the ApoE4 genetic variant
- Certain bacterial infections
- Vascular risk factors (e.g., diabetes, atherosclerosis, high blood pressure, high cholesterol) appear to encourage the development of phenomena associated with Alzheimer’s disease such as accumulation of amyloid beta (Kalaria 2012).
- History of head trauma
- High homocysteine levels
- Nutrient deficiencies
- Silent strokes
- Central obesity (i.e., high waist-to-hip ratio)