Alzheimer’s Disease
References
ADEAR (Alzheimer's Disease Education & Referral Center). Alzheimer’s disease: unraveling the mystery. 2004. Silver Spring, Md: Department of Health and Human Services. Available at: http://www.alzheimers.org/unraveling/index.htm. Accessed July 31, 2004.
Aggarwal BB, Shishodia S. Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning. Ann N Y Acad Sci. 2004 Dec;1030:434-41.
Akbar M, Calderon F, et al. Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10858-63.
Almeida OP, Flicker L. Testosterone and dementia: too much ado about too little data. J Br Menopause Soc. 2003;9(3):107-10.
Ames BN, Liu J. Delaying the mitochondrial decay of aging with acetylcarnitine. Ann N Y Acad Sci. 2004 Nov;1033:108-16.
Bai DL, Tang XC, et al. Huperzine A: a potential therapeutic agent for treatment of Alzheimer's disease. Curr Med Chem. 2000;7(3):355-74.
Baum L, Ng A. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models. J Alzheimers Dis. 2004 Aug;6(4):367-77.
Bidzan L, Biliekiewicz A, et al. Preliminary assessment of ginkgo biloba (Ginkofar) in patients with dementia [in Polish]. Psychiatr Pol. 2005 May-Jun;39(3):559-66.
Boothby LA, Doering PL. Vitamin C and vitamin E for Alzheimer's disease. Ann Pharmacother. 2005 Dec;39(12):2073-80.
Borek C. Garlic reduces dementia and heart-disease risk. J Nutr. 2006 Mar;136(3):810S-2S.
Brinton RD. Investigative models for determining hormone therapy-induced outcomes in brain: evidence in support of a healthy cell bias of estrogen action. Ann N Y Acad Sci. 2005 Jun;1052:57-74.
Butterworth RF. Evidence for forebrain cholinergic neuronal loss in congenital ornithine transcarbamylase deficiency. Metab Brain Dis. 2000 Mar;15(1):83-91.
Cheng DH, Ren H, et al. Huperzine A: a novel promising acetylcholinesterase inhibitor. Neuroreport. 1996;8(1):97-101.
Cheng Y, Feng Z, et al. Beneficial effects of melatonin in experimental models of Alzheimer disease. Acta Pharmacol Sin. 2006 Feb;27(2):129-39.
Cherrier MM, Matsumoto AM, et al. Testosterone improves spatial memory in men with Alzheimer disease and mild cognitive impairment. Neurology. 2005 Jun 28;64(12):2063-8.
Choudhary MI, Yousuf S, et al. Cholinesterase inhibiting withanolides from Withania somnifera. Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1358-61.
Ciabattoni G, Porreca E, et al. Determinants of platelet activation in Alzheimer's disease. Neurobiol Aging. 2006 Jan 23; [Epub ahead of print].
Cole GM, Morihara T, et al. NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models. Ann N Y Acad Sci. 2004 Dec;1035:68-84.
Crack PJ, Cimdins K, et al. Lack of glutathione peroxidase-1 exacerbates Abeta-mediated neurotoxicity in cortical neurons. J Neural Transm. 2005 Oct 21;[Epub ahead of print]
Crook T, Petrie W, et al. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull. 1992;28(1):61-6.
Darvesh S, Arora RC, et al. Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons. Exp Neurol. 2004;188(2):461-70.
de Jesus Moreno Moreno M. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clin Ther. 2003 Jan;25(1):178-93.
Dhanasekaran M, Ren J. The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus. Curr Neurovasc Res. 2005 Dec;2(5):447-59.
Dhitavat S, Ortiz D, et al. Folate, vitamin E, and acetyl-L-carnitine provide synergistic protection against oxidative stress resulting from exposure of human neuroblastoma cells to amyloid-beta. Brain Res. 2005 Nov 9;1061(2):114-7.
Diamond BJ, Shiflett SC, et al. Ginkgo biloba extract: mechanisms and clinical indications. Arch Phys Med Rehab. 2000;81(5):668-78.
Engelborghs S, Vloeberghs E, et al. Correlations between cognitive, behavioural and psychological findings and levels of vitamin B12 and folate in patients with dementia. Int J Geriatr Psychiatry. 2004;19(4):365-70.
Farr SA, Banks WA, et al. DHEAS improves learning and memory in aged SAMP8 mice but not in diabetic mice. Life Sci. 2004 Oct 22;75(23):2775-85.
Galbusera C, Facheris M, et al. Increased susceptibility to plasma lipid peroxidation in Alzheimer disease patients. Curr Alzheimer Res. 2004 May;1(2):103-9.
Grundman M. Vitamin E and Alzheimer disease: the basis for additional clinical trials. Am J Clin Nutr. 2000 Feb;71(2):630S-6S.
Hashimoto M, Tanabe Y, et al. Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid beta-infused rats. J Nutr. 2005 Mar;135(3):549-55.
Heinen-Kammerer T, Motzkat K, et al. The situation of patients with dementia may be rectified by Ginkgo biloba: results of a health services research study concerning the ability of patients with dementia, quality of life of the nursing family members and total treatment costs [in German]. MMW Fortschr Med. 2005 Oct 6;147(suppl 3):127-33.
Hillen T, Lun A, et al. DHEA-S plasma levels and incidence of Alzheimer's disease. Biol Psychiatry. 2000;47(2):161-3.
Hogervorst E, Combrinck M, et al. Testosterone and gonadotropin levels in men with dementia. Neuro Endocrinol Lett. 2003;24(3-4):203-8.
Joseph JA, Shukitt-Hale B, et al. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci. 1999 Sep 15;19(18):8114-21.
Kado DM, Karlamangla AS, et al. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med. 2005 Feb;118(2):161-7.
Kasper DL, Braunwald E, et al, eds. Harrison’s Principles of Internal Medicine. 16th ed. New York, NY: McGraw-Hill; 2004.
Kidd PM. Neurodegeneration from mitochondrial insufficiency: nutrients, stem cells, growth factors, and prospects for brain rebuilding using integrative management. Altern Med Rev. 2005 Dec;10(4):268-93.
Kidd P. Phosphatidylserine: Nature’s Brain Booster for Memory, Mood, and Stress. Total Health Communications, Inc.; 2005.
Klinkhammer P, Szelies B, et al. Effect of phosphatidylserine on cerebral glucose metabolism in Alzheimer’s disease. Dementia. 1990;1:197-201.
Kuboyama T, Tohda C, et al. Neuritic regeneration and synaptic reconstruction induced by withanolide A. Br J Pharmacol. 2005 Apr;144(7):961-71.
Kyle DJ, Schaefer E, et al. Low serum docosahexaenoic acid is a significant risk factor for Alzheimer's dementia. Lipids. 1999;34(suppl):S245.
Landmark K. Could intake of vitamins C and E inhibit development of Alzheimer dementia [in Norwegian]? Tidsskr Nor Laegeforen. 2006 Jan 12;126(2):159-61.
Lau FC, Shukitt-Hale B, et al. The beneficial effects of fruit polyphenols on brain aging. Neurobiol Aging. 2005 Dec;26(suppl 1):128-32.
Li MH, Jang JH, et al. Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death. Ann NY Acad Sci. 2004 Dec;1030:317-29.
Lu PH, Masterman DA, et al. Effects of testosterone on cognition and mood in male patients with mild Alzheimer disease and healthy elderly men. Arch Neurol. 2006 Feb;63(2):177-85.
Lukiw WJ, Cui JG, et al. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest. 2005 Oct;115(10):2774-83.
Mandel S, Amit T, et al. Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders. Mol Nutr Food Res. 2006 Feb;50(2):229-34.
Mas E, Dupuy AM, et al. Functional vitamin E deficiency in apoE4 patients with Alzheimer's disease. Dement Geriatr Cogn Disord. 2006;21(3):198-204.
Mayo W, George O, et al. Individual differences in cognitive aging: implication of pregnenolone sulfate. Prog Neurobiol. 2003 Sep;71(1):43-8.
Mayo W, Lemaire V, et al. Pregnenolone sulfate enhances neurogenesis and PSA-NCAM in young and aged hippocampus. Neurobiol Aging. 2005 Jan;26(1):103-14.
McCann SM, Mastronardi C, et al. The nitric oxide theory of aging revisited. Ann N Y Acad Sci. 2005 Dec;1057:64-84.
Mizrahi EH, Jacobsen DW, et al. Plasma total homocysteine levels, dietary vitamin B6 and folate intake in AD and healthy aging. J Nutr Health Aging. 2003;7(3):160-5.
Moreira PI, Santos MS, et al. CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats. Exp Neurol. 2005 Nov;196(1):112-9.
Morris MC, Evans DA, et al. Dietary niacin and the risk of incident Alzheimer's disease and of cognitive decline. J Neurol Neurosurg Psychiatry. 2004 Aug;75(8):1093-9.
Mulder C, Scheltens P, et al. Low vitamin B6 levels are associated with white matter lesions in Alzheimer's disease. J Am Geriatr Soc. 2005 Jun;53(6):1073-4.
Ono K, Hasegawa K, et al. Preformed beta-amyloid fibrils are destabilized by coenzyme Q10 in vitro. Biochem Biophys Res Commun. 2005 Apr 29;330(1):111-6.
Pennanen C, Laakso MP, et al. Serum testosterone levels in males with Alzheimer's disease. J Neuroendocrinol. 2004;16(2):95-8.
Pereira C, Agostinho P, et al. Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models [in Portuguese]. Acta Med Port. 2003 Nov-Dec;16(6):401-6.
Perry EK, Pickering AT, et al. Medicinal plants and Alzheimer's disease: from ethnobotany to phytotherapy. J Pharm Pharmacol. 1999;51(5):527-34.
Pocernich CB, La Fontaine M, et al. In vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain. Neurochem Int. 2000;36(3):185-91.
Polleri A, Gianelli MV, et al. Dementia: a neuroendocrine perspective. J Endocrinol Invest. 2002;25(1):73-83.
Quadri P, Fragiacomo C, et al. Homocysteine and B vitamins in mild cognitive impairment and dementia. Clin Chem Lab Med. 2005;43(10):1096-100.
Ravaglia G, Forti P, et al. Homocysteine and folate as risk factors for dementia and Alzheimer disease. Am J Clin Nutr. 2005 Sep;82(3):636-43.
Reiter RJ, Cabrera J, et al. Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and parkinsonism. Ann NY Acad Sci. 1999;890:471-85.
Rezai-Zadeh K, Shytle D, et al. Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. J Neurosci. 2005 Sep 21;25(38):8807-14.
Ringman JM, Frautschy SA, et al. A potential role of the curry spice curcumin in Alzheimer's disease. Curr Alzheimer Res. 2005 Apr;2(2):131-6.
Schneider LS, DeKosky ST, et al. A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type. Curr Alzheimer Res. 2005 Dec;2(5):541-51.
Schumacher M, Guennoun R, et al. Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination. Growth Horm IGF Res. 2004 Jun;14(suppl A):S18-S33.
Serot JM, Christmann D, et al. CSF-folate levels are decreased in late-onset AD patients. J Neural Transm. 2001;108(1):93-9.
Shi J, Yu J, et al. Polyphenolics in grape seeds: biochemistry and functionality. J Med Food. 2003;6(4):291-9.
Singh M. Mechanisms of progesterone-induced neuroprotection. Ann N Y Acad Sci. 2005 Jun;1052:145-51.
Szilagyi G, Nagy Z, et al. Effects of vinpocetine on the redistribution of cerebral blood flow and glucose metabolism in chronic ischemic stroke patients: a PET study. J Neurol Sci. 2005 Mar 15;229-230:275-84.
Tang XC. Huperzine A (shuangyiping): a promising drug for Alzheimer's disease. Zhongguo Yao Li Xue Bao. 1996 Nov;17(6):481-4.
Tchantchou F, Graves M, et al. N-acetyl cysteine alleviates oxidative damage to central nervous system of ApoE-deficient mice following folate and vitamin E-deficiency. J Alzheimers Dis. 2005 Apr;7(2):135-8.
Tucker KL, Qiao N, et al. High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Am J Clin Nutr. 2005 Sep;82(3):627-35.
Virmani MA, Caso V, et al. The action of acetyl-L-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones. Ann N Y Acad Sci. 2001 Jun;939:162-78.
Wang HX, Wahlin A, et al. Vitamin B(12) and folate in relation to the development of Alzheimer's disease. Neurology. 2001 May 8;56(9):1188-94.
Wang JZ, Wang ZF. Role of melatonin in Alzheimer-like neurodegeneration. Acta Pharmacol Sin. 2006 Jan;27(1):41-9.
Wang LM, Han YF, et al. Huperzine A improves cognitive deficits caused by chronic cerebral hypoperfusion in rats. Eur J Pharmacol. 2000;398(1):65-72.
Wang R, Yan H, et al. Progress in studies of huperzine A: a natural cholinesterase inhibitor from Chinese herbal medicine. Acta Pharmacol Sin. 2006 Jan;27(1):1-26.
Webber KM, Casadesus G, et al. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Ann N Y Acad Sci. 2005 Jun;1052:201-9.
Weill-Engerer S, David JP, et al. Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients. J Clin Endocrinol Metab. 2002;87(11):5138-43.
Wu X, Beecher GR, et al. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37.
Xu SS, Gao ZX, et al. Efficacy of tablet huperzine-A on memory, cognition, and behavior in Alzheimer's disease. Zhongguo Yao Li Xue Bao. 1995 Sep;16(5):391-5.
Yang F, Lim GP, et al. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. J Biol Chem. 2005 Feb 18;280(7):5892-901.
Yao ZX, Han Z, et al. Ginkgo biloba extract (Egb 761) inhibits beta-amyloid production by lowering free cholesterol levels. J Nutr Biochem. 2004 Dec;15(12):749-56.
Young G, Conquer J. Omega-3 fatty acids and neuropsychiatric disorders. Reprod Nutr Dev. 2005 Jan;45(1):1-28.
Zandi PP, Anthony JC, et al. Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. Arch Neurol. 2004;61(1):82-8.
Zhang Z, Wang X, et al. Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease: a placebo-controlled, double-blind, randomized trial [in Chinese]. Zhonghua Yi Xue Za Zhi. 2002;82(14):941-4.