180 capsules: Thorne Research, Item# 25157
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Pyridoxine, also known as vitamin B6, is necessary for the transformation and utilization of amino acids for many functions in the body, including energy production and neurotransmitter synthesis. Vitamin B6 is also involved in the production of hemoglobin, intrinsic factor, and is a vital component in the formation of the myelin sheath that surrounds nerve cells. But in order for pyridoxine to be used by the body it must first be converted to pyridoxal 5'-phosphate (P5P), a process that takes place in the liver. Individuals with compromised liver function have difficulty making this conversion and consequently may be at risk of a vitamin B6 deficiency. Supplementing with pyridoxal 5'-phosphate ensures the most bioactive form of vitamin B6.
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Doses of vitamin B6 above 200 mg may inhibit breast milk production. High dose vitamin B6 supplementation (as pyridoxine HCl >500 mg daily long term) has resulted in reversible neuropathies in some individuals. There have been no case reports of neuropathies with pyridoxal 5'-phosphate use.
If pregnant, consult your health-care practitioner before using this product. This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.