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What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today

What's Hot features original summaries of the latest peer-reviewed journal articles published in the fields of longevity, dietary supplements, health and wellness, and nutrition. Access the latest news concerning nutritional supplements and vitamins online at What's Hot each Monday, Wednesday and Friday. Articles are archived by month and year of publication for easy retrieval. What's Hot reports exciting findings on everything from the vitamins and supplements you and your family use on a daily basis to advanced high tech breakthroughs in the field of gerontology.

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What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today

Progeria finding suggests promise for sulforaphane in aging research

Progeria finding suggests promise for sulforaphane in aging researchDecember 19 2014. A report published online on December 16, 2014 in the journal Aging Cell describes new findings in the field of the premature aging disorder known as Hutchinson-Gilford progeria syndrome (HGPS). The disease is caused by mutations in the LMNA gene that lead to the formation of a defective protein that is referred to as progerin. Due to progerin's nonfunctionality, it accumulates in the cell nucleus, resulting in cellular aging and the development of aging-associated diseases in its young victims, including osteoporosis and atherosclerosis.

Professor Karima Djabali and her colleagues at Germany's Technische Universität München determined that both healthy cells and those with the HGPS mutations contain progerin, although in HGPS, the amount is notably higher.

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