Life Extension Final Clerance Sale

What's Hot

What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today

What's Hot features original summaries of the latest peer-reviewed journal articles published in the fields of longevity, dietary supplements, health and wellness, and nutrition. Access the latest news concerning nutritional supplements and vitamins online at What's Hot each Monday, Wednesday and Friday. Articles are archived by month and year of publication for easy retrieval. What's Hot reports exciting findings on everything from the vitamins and supplements you and your family use on a daily basis to advanced high tech breakthroughs in the field of gerontology.

We invite you to browse the What's Hot archive to view past headlines in the areas of nutrition, health and wellness that the majority of the public are still unaware of.

What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today

Curcumin could help fight mesothelioma

Curcumin could help fight mesothelioma

September 22 2014. Malignant mesothelioma, a cancer of the lining of the lungs that is largely attributable to asbestos exposure, could face a worthy opponent in the form of curcumin, a compound that occurs in the spice turmeric, according to research reported in October 2014 issue of Clinical Cancer Research.

Ashfin Dowlati and colleagues at University Hospitals Case Medical Center in Cleveland measured mesothelioma tumor expression of PIAS3 (protein inhibitor of activated STAT3), which is correlated with overall survival. They additionally evaluated the effects of PIAS3 activity on the intracellular protein and transcription factor STAT3 (signal transducer and activator of transcription 3), which can trigger cancer onset and growth. “In those mesothelioma patients where PIAS3 is low, indeed STAT3 is activated,” reported Dr Dowlati. “Mesothelioma patients who have low PIAS3 and high STAT3 have a greater chance of dying early. On the flip side, those patients with a high PIAS3 levels have a 44 percent decreased chance of dying in one year, which is substantial.”
The team found that STAT3 down regulation, via enhanced expression of PIAS3 or exposure to a peptide derived from PIAS3, inhibited cell growth and increased apoptosis. Administration of curcumin resulted in PIAS3 induction, indicating a potential role for the compound in mesothelioma therapy.

Recent What's Hot Articles

Vitamins and supplements news are posted here frequently to keep you up-to-date with the latest advances in health and wellness. We have an unparalleled track record of breaking stories about dietary supplements and life extension advances.

August 2014

What's Hot 

Meta-analysis associates moderate coffee drinking with lower risk of dying over up to two decades

July 2014

What's Hot 

Study sheds light on tamoxifen resistance

June 2014

What's Hot 

Fish oil use associated with brain volume preservation

May 2014

What's Hot 

Physicians recommend cardiovascular safety data requirement for blood pressure-elevating drugs

April 2014

What's Hot 

Greater vitamin D levels associated with longer cancer remission and survival

March 2014

What's Hot 

Lifestyle improvement may be as influential as drug therapy for ED

What's Hot Archive

​​​​​​​