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Super Ubiquinol CoQ10 with BioPQQ®

100 mg 30 softgels, Item# 01733

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Super Ubiquinol CoQ10 with BioPQQ®
100 mg 30 softgels
Item Catalog Number: 01733

Life Extension® continues to develop increasingly potent mitochondria-boosting formulations.1-4 The new Super Ubiquinol CoQ10 with BioPQQ® contains shilajit (which studies have shown doubles CoQ10 levels in the mitochondria) plus the breakthrough compound PQQ (shown to support the spontaneous generation of new mitochondria in aging cells). This represents a three-way strategy for enhanced mitochondrial support.

1. Super Ubiquinol CoQ10

CoQ10 is required to convert the energy from fats and sugars you eat into usable cellular energy. More people are supplementing with CoQ10 than ever before. A key reason is increased awareness that the body’s production of CoQ10 declines significantly with advancing age.5 Statin drugs also deplete CoQ10 levels in the blood, and possibly, tissues.6,7 For example, statin drugs reduce plasma CoQ10 by almost 40%—but the aging process itself reduces CoQ10 levels in the heart muscle wall by 72%.8

Studies show that absorption of the ubiquinol form of CoQ10 is far greater than the conventional ubiquinone form. In middle-aged mice, ubiquinol was shown to be 40% more effective in slowing measurements of aging, compared to ubiquinone.9 Life Extension® offers this highly bioavailable ubiquinol form of patented CoQ10 in an advanced delivery system, providing an unparalleled absorption level.10

2. Enhanced Support with Shilajit

PrimaVie® shilajit has been shown to double levels of CoQ10 in mitochondria.11 Combining CoQ10 and shilajit produced a 56% increase in energy production in the brain—40% better than CoQ10 alone. And in muscle, there was a 144% increase in energy production—27% better than CoQ10 alone.12

Shilajit boosts CoQ10’s beneficial effects by stabilizing CoQ10 in the superior ubiquinol form.13,14 Additionally, shilajit facilitates more efficient delivery of CoQ10 into the mitochondria, which results in greater cellular energy production.15-18 Shilajit itself is rich in essential compounds that help the mitochondria convert fats and sugars into ATP (adenosine triphosphate), the body’s main source of energy.16

3. PQQ Promotes Growth of New Mitochondria

Until recently, the only options for aging individuals to promote replenishment of the declining numbers of mitochondria in their bodies were long-term calorie restriction or exhaustive physical activity—difficult or impractical for most aging people. Now PQQ offers a viable alternative: PQQ (pyrroloquinoline quinone) promotes spontaneous production of new mitochondria.19 In fact, PQQ promotes youthful cellular function in three distinct ways:

  • Promotes mitochondrial biogenesis. PQQ activates genes that promote the formation of fresh mitochondria.19 It also beneficially interacts with genes directly involved in mitochondrial health. These same genes support healthy body weight, normal fat and sugar metabolism and youthful cellular proliferation.20
  • Mitochondrial defense. Mitochondria possess their own DNA, distinct from those contained in the cell nucleus. Unfortunately, compared to nuclear DNA, mitochondrial DNA are relatively unprotected—and yet situated at the source of both energy and free-radical production. PQQ’s antioxidant potency and favorable gene-expression profile powerfully boost mitochondrial defense.
  • Antioxidant power. PQQ is a potent antioxidant. Its extraordinary molecular stability enables it to facilitate thousands of antioxidant reactions in the mitochondria—without breaking down—for maximum antioxidant and bioenergetic support.21

PQQ is an essential nutrient, meaning that your body cannot make it on its own. A wealth of research demonstrates that—alone and especially in combination with CoQ10—its unique nutritional profile supports heart health and brain function.22-24 This should be no surprise, given how much energy these vital organs need.

Life Extension® has identified a purified, highly potent form of PQQ from Japan that is produced through a unique fermentation process. The result is some of the highest quality PQQ available today.

The optimal dose of PQQ is 20 mg each day. Members taking Mitochondrial Energy Optimizer, Mitochondrial Basics, or PQQ 10 mg caps obtain this optimal PQQ dose when taking the new Super Ubiquinol CoQ10 with PQQ.

References
1. Curr Alzheimer Res. 2011 Dec;8(8):868-75.
2. Dev Disabil Res Rev. 2010 Jun;16(2):183-8
3. N Z Med J. 2009 Oct 30;122(1305):74-9.
4. Mol Genet Metab. 2004 Apr;81(4):263-72.
5. Mech Ageing Dev. 2010 Apr;131(4):225-35.
6. Mitochondrion. 2007 Jun;7 Suppl:S168-74.
7. Cardiol Rev. 2005 Mar-Apr;13(2):76-9.
8. Biofactors. 1999;9(2-4):291-9.
9. Exp Gerontol. 2006 Feb;41(2):130-40.
10. Regul Toxicol Pharmacol. 2007 Feb;47(1):19-28.
11. Systemic CoQ level in animals: Part II. Unpublished study. Natreon, Inc.:2007.12.
12. Pharmacologyonline. 2009;1:817-25.
13. Pharmacologyonline. 2009;2:690-8.
14. Electron J Biotechn. 2008 Jul 15;11(3).
15. Environ Sci Technol. 2002 Jul 15;36(14):3170-5.
16. Environ Sci Technol. 2009 Feb 1;43(3):878-83.
17. Environ Sci Technol. 2002 May 1;36(9):1939-46.
18. Ghosal S. Shilajit in Perspective. Alpha Science International Limited; 2006.
19. J Biol Chem. 2010 Jan 1;285:142-52.
20. Available at: http://www.ncbi.nlm.nih.gov/gene/10891 . Accessed May 21, 2013.
21. Alt Med Rev. 2009; 14(3):268-77.
22. Cardiovasc Drugs Ther. 2004 Nov;18(6):421-31.
23. J Cardiovasc Pharmacol Ther. 2006 Jun;11(2):119-28.
24. FOOD Style. 2009;21:13(7)50-3.
Supplement Facts

Serving Size 1 softgel

Servings Per Container 30

Amount Per Serving

Calories

5

Calories from Fat

5

Total Fat

0.5 g

Ubiquinol (as Kaneka QH® Ubiquinol)

100 mg

PrimaVie® Shilajit fulvic acid complex

100 mg

BioPQQ® Pyrroloquinoline quinone disodium salt

10 mg

Other ingredients: medium chain triglycerides oil, gelatin, glycerin, purified water, sunflower lecithin, annatto color, beeswax, rosemary extract.

Kaneka QH® is a registered trademark of Kaneka Corporation.
PrimaVie® is a registered trademark of Natreon, Inc.
BioPQQ® is a registered trademark of MGC (Japan).

Dosage and Use
  • Take one softgel daily with food, or as recommended by a healthcare practitioner.
Warnings

REVIEW SNAPSHOT®

by PowerReviews
Life ExtensionSuper Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels
 
4.3

(based on 6 reviews)

Ratings Distribution

  • 5 Stars

     

    (4)

  • 4 Stars

     

    (1)

  • 3 Stars

     

    (0)

  • 2 Stars

     

    (1)

  • 1 Stars

     

    (0)

100%

of respondents would recommend this to a friend.

Pros

  • Simple to take (5)
  • No side effects (4)

Cons

    Best Uses

    • Daily use (5)
    • Older people (4)
    • Women (4)
    • Men (3)
      • Reviewer Profile:
      • Health conscious (3), Regular user (3)

    Reviewed by 6 customers

    Sort by

    Displaying reviews 1-6

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    5.0

    I will continue to buy this product.

    By Timespast

    from Oklahoma short grass country.

    About Me Medical Professional

    See all my reviews

    Pros

    • Does Not Upset Stomach
    • No Side Effects
    • Simple To Take

    Cons

    • No Cons With Product

    Best Uses

    • Daily Use
    • Men
    • Older People
    • Women

    Comments about Life Extension Super Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels:

    I take this supplement once daily in the morning. It
    seems to boost my energy level. Will continue to use this supplement.

    Comment on this review

     
    5.0

    I've taken it forever!

    By Connie

    from Scottsdale, AZ

    About Me Regular User

    See all my reviews

    Pros

    • No Side Effects
    • Simple To Take

    Cons

      Best Uses

      • Daily Use

      Comments about Life Extension Super Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels:

      I use it to stay healthy at 81.

      Comment on this review

      (0 of 2 customers found this review helpful)

       
      2.0

      Dissapointed,but would work for others

      By GG Cris

      from RIO RICO,AZ

      About Me Health Conscious

      See all my reviews

      Pros

      • Acts Quickly
      • Simple To Take

      Cons

      • Causes Side Effects
      • Irritated My Stomach

      Best Uses

      • Used It Every Other Day

      Comments about Life Extension Super Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels:

      At the beginning, tried to use it every day,but could not handle it.The ingredients shown on label are GOOD,but did not agree with my digestive system.I'm sure this product would do wonders to those able to digest it.Life Extension's service and delivery are EXCELLENT!

      Comment on this review

       
      4.0

      Powerful Formula

      By Blondebroker

      from San Diego, CA

      About Me First Time User, Health Conscious

      Pros

      • No Side Effects
      • Produces Results

      Cons

      • Complicated To Take

      Best Uses

      • Daily Use
      • Older People
      • Women

      Comments about Life Extension Super Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels:

      I have great difficulty swallowing pills. Therefore, I cut the softgel open and put it in my evening cocoa. It would be wonderful to have this powerful formula in a chewable form. I am actively trying to fight the inevitable signs of ageing. Your magazine is so pertinent for todays
      ageing population. I am still quite healthy for my age (77) but I wish I had started on my health conscious regimens decades ago.

      Comment on this review

       
      5.0

      Convenience in a Small Package

      By Road Doctor

      from Maryland's Eastern Shore

      About Me Health Conscious, Medical Professional, Regular User

      See all my reviews

      Pros

      • A Small And Convenient Co
      • Simple To Take

      Cons

        Best Uses

        • Daily Use
        • Men
        • Older People
        • Women

        Comments about Life Extension Super Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels:

        I have been a fan of Q10 for many years and seen its results when used by many. PQQ is a "new kid on the block", but seems to have great potential. To have the two combined is really convenient and probably cost effective as well. I will continue to purchase the combination and recommend it to others.

        Comment on this review

        (10 of 10 customers found this review helpful)

         
        5.0

        The Ultimate CoQ10 Formula?

        By Vitamin Pro

        from Florham Park, NJ

        About Me Regular User

        See all my reviews

        Pros

        • Acts Quickly
        • No Side Effects
        • Simple To Take

        Cons

          Best Uses

          • Daily Use
          • Men
          • Older People
          • Women

          Comments about Life Extension Super Ubiquinol CoQ10 with BioPQQ®, 100 mg 30 softgels:

          Having been in the nutritional supplement industry for 20 years, and seeing virtually every CoQ10 formula available during this time, I have to say this new formula with the extraordinary PQQ and Shilajit is the premier product of its kind.

          PQQ works synergistically with CoQ10 for ATP synthesis and protection of the mitochondria against oxidative damage (especially of the mitochondrial DNA). PQQ has also been scientifically validated for creation of mitochondrial biogenesis (the creation of brand new mitochondria)...regardless of your age.

          Shilajit significantly boosts levels of CoQ10 inside the cells - even if you already have sufficient levels of CoQ10!

          Leave it to LEF to be the first to market with the "Co10 trifecta".

          I personally will recommend this product to every person I know that takes CoQ10.

          Comment on this review

          Displaying reviews 1-6

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