The requested item LC142005 is obsolete and has been replaced. The new item is LC100031.

Galectin-3 with NT-proBNP

Item# LC100031

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  • Galectin-3 with NT-proBNP
  • Item Catalog Number: LC100031

Are you worried about developing cardiovascular disease, Alzheimer’s, arthritis or cancer?  A key new biomarker is on the stage to help you gain an accurate picture of your risk for these degenerative diseases and it’s called Galectin-3

We all know what happens when we cut ourselves…our skin thickens and the healing process forms a scar. But what about internal scarring due to inflammation? Our bodies react in the same way they do when we cut ourselves, forming excess tissue. But remember, there is no cut….only inflammation! This internal scarring process is called fibrosis, which can stiffen tissue and damage organs…especially the heart!

Fibrosis of the heart can lead to heart failure which means the heart isn’t working efficiently. Heart failure does not mean the heart stops beating!  In 2012 the CDC estimated that 5.8 million people in the United States have heart failure and is one of the most common reasons people aged 65 and over are hospitalized.1 Since we know that Galectin-3 causes fibrosis, it’s imperative for you to take this simple blood test to identify early stages of heart failure…while there is still time to intervene!

Another well-known function of Galectin-3 is its role in the formation and metastasis of cancerous tumors. It serves as the main mechanism by which cancers grow rapidly and spread throughout your body. Since Galectin-3 can actually trigger the harmful changes which increase your risk for cancer, it’s a blood test that you don’t want to do without!

Concerned with longevity and quality of life?  In 2011, a groundbreaking Galectin-3 study involving over 8,000 people was presented at a European conference. The results of this study showed that elevated serum Galectin-3 increased overall mortality three-fold in the general population.2 So not only is Galectin-3 a valuable biomarker for early stage, symptomless heart disease and cancer it is important for everyone who is concerned with their quality of life!

If we think of Galectin-3 as a trigger for fibrosis that leads to heart disease and cancer, along with other inflammatory degenerative diseases, then it makes sense to add a second biomarker that gives focus to our heart’s structure and function.

This N-terminal fragment of the prohormone BNP is a highly sensitive marker for cardiac dysfunction. An elevated NT-proBNP level always indicates the presence of an underlying cardiac disorder. It can even identify people with structural heart disease and cardiac dysfunction before symptoms begin.3  Even relatively low levels of NT-proBNP may be considered an index of increased cardiovascular risk since NT-proBNP abnormalities correlate well with development of progressive atherosclerosis.4

These unsuspecting people are at high risk for future cardiac events…and they don’t even know it! Don’t be one of them…measure your level of NT-proBNP and know for sure! Because the good news is that a normal level of NT-proBNP virtually excludes cardiac dysfunction!

Fasting is not required. Take your medication as prescribed.

  1. National Heart Lung and Blood Institute. People Science Health. What is heart failure? [Accessed February 2012].
  2. Rudolf A. deBoer, Dirk J. Van Veldhuisen, Ron T. Gansevoort, Anneke C. Muller Kobold, Herman H.W. Silljé, Wiek H. Van Gilst, Hans L. Hillege, Stephan J.L. Bakker, Pim Van Der Harst. (2011). Galectin-3, cardiovascular risk factors, and outcome in the general population.  
  3. Mueller T, Gegenhuber A, Poelz W, Haltmayer M. Head-to-head comparison of the diagnostic utility of BNP and NT-proBNP in symptomatic and asymptomatic structural heart disease. Clin Chim Acta 2004 March;341(1-2):41-8.
  4. Seino Y, Ogawa A, Yamashita T et al. Application of NT-proBNP and BNP measurements in cardiac care: a more discerning marker for the detection and evaluation of heart failure. Eur J Heart Fail 2004 March 15;6(3):295-300.

The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.