Daily News: Aging

Reports from Fuwai Hospital Highlight Recent Findings in Clinical Chemistry

NewsRx.com

04-12-13

By a News Reporter-Staff News Editor at Cardiovascular Week -- Fresh data on Clinical Chemistry are presented in a new report. According to news reporting out of Beijing, People's Republic of China, by NewsRx editors, research stated, "Pregnancy-associated plasma protein-A (PAPP-A), a newly discovered member of insulin like growth factors (IGFs) axis, has been reported to be a biomarker in both cardiac and non-cardiac conditions. PAPP-A mainly acts as a protease cleaving IGF inhibitors - IGF binding proteins (IGFBPs), thereby setting free IGFs."

Our news journalists obtained a quote from the research from Fuwai Hospital, "In cardiac conditions, PAPP-A plays an important role in progressive atherosclerosis. As a biomarker, PAPP-A is not only sensitive, specific and early for diagnosis of acute coronary syndrome, but also an independent risk factor for all-cause mortality or combined cardiovascular events. In non-cardiac conditions, PAPP-A is a new anti-aging target. PAPP-A knock out (KO) mice have a prolonged lifespan than the wild type."

According to the news editors, the research concluded: "In addition, PAPP-A is also a biomarker associated with malignant cancer and end stage renal disease."

For more information on this research see: PAPP-A in cardiac and non-cardiac conditions. Clinica Chimica Acta, 2013;417():67-72. Clinica Chimica Acta can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Clinica Chimica Acta - www.elsevier.com/wps/product/cws_home/506018)

Our news journalists report that additional information may be obtained by contacting Y.H. Li, Fuwai Hosp, Natl Center Cardiovasc Dis, Anesthesiol Div, Beijing 100037, People's Republic of China (see also Clinical Chemistry).

Keywords for this news article include: Asia, Beijing, Cardiology, Clinical Chemistry, People's Republic of China

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