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This panel contains the following tests:
D-dimer is a test that measures the tendency of blood to clot inappropriately. The higher the number, the greater the risk for conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and arterial plaque rupture.
Life Extension® believes if you are prone to clotting, you are at greater risk for heart disease and stroke. D-dimer may be ordered when you have symptoms of DVT, such as leg pain, tenderness, swelling, discoloration, edema … or symptoms of PE, such as labored breathing, coughing, and lung-related chest pain.
A sub analysis of RE-LY trial data presented at a 2010 conference of the American Heart Association indicates that D-dimer level at baseline appears to be an independent predictor of risk for cardiovascular events including stroke. A baseline D-dimer concentration of less than 298 µg/L was associated with a 1.4% rate of stroke or systemic embolism while baseline D-dimer of 823 µg/L or more was associated with a nearly threefold increase in risk, according to John Eikelboom, MBBS, MSc, of the Population Health Research Institute in Hamilton, Ontario (Eikelboom, J et al. American Heart Association 2010; Abstract 18321).
Doctors also like to check coagulation profiles which include PT and PTT. PT stands for Prothrombin Time and PTT stands for Partial Thromboplastin Time. They are measurements of how quickly a blood clot forms. These tests may be ordered when people present with unexplained bleeding or bruising or with chronic conditions such as liver disease or lupus.
Fibrinogen, a protein produced by the liver, plays a role in the development of arterial plaque and can also cause acute blood clots. The formation of acute blood clots can initiate a heart attack or stroke.
This test also contains an INR (International Normalized Ratio) for those people taking Coumadin. Doctors use an INR to assess the effect of the drug.
Fasting is not required for this test. Take all medications as prescribed.
The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.
Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.