What's Hot

What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today

What's Hot features original summaries of the latest peer-reviewed journal articles published in the fields of longevity, dietary supplements, health and wellness, and nutrition. Access the latest news concerning nutritional supplements and vitamins online at What's Hot each Monday, Wednesday and Friday. Articles are archived by month and year of publication for easy retrieval. What's Hot reports exciting findings on everything from the vitamins and supplements you and your family use on a daily basis to advanced high tech breakthroughs in the field of gerontology.

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What's Hot in Nutrition, Dietary Supplements, Health and Wellness Today

Analysis affirms vitamin E's effectiveness in NASH

Analysis affirms vitamin E's effectiveness in NASHApril 24 2015. The International Liver Congress™ 2015 was the site of a presentation on April 23 of the outcome of an analysis of three clinical trials which affirmed a benefit for D-alpha-tocopherol treatment of nonalcoholic steatohepatitis (NASH), a serious liver condition. NASH is characterized by inflammation of the liver due to fat accumulation, and is preceded by nonalcoholic fatty liver disease, which affects approximately a third of the U.S. population,  

The analysis included participants in the PIVENS trial, which compared vitamin E to pioglitazone and a placebo in nondiabetic adults; TONIC, which compared vitamin E to metformin and placebo in nondiabetic children, and FLINT, which compared diabetics and nondiabetics given obeticholic acid to a placebo group, some of whom were supplementing with vitamin E.  Among 155 NASH patients treated with vitamin E, histologic improvement was more than twice as likely to occur in comparison with 192 patients who did not receive the vitamin. While 20% of those who did not receive vitamin E experienced resolution of their disease, resolution occurred in 38% of vitamin-treated patients. Cardiac events and lipid changes were similar among both groups.

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